Duchenne muscular dystrophy (DMD) is a devastating, rare disease. While clinically
described in the 19 th century, the genetic foundation of DMD was not discovered until more …

In the last years, magnetic resonance imaging (MRI) has become fundamental for the
diagnosis and monitoring of myopathies given its ability to show the severity and distribution …

Objective To identify the best quantitative fat–water MRI biomarker for disease progression
of leg muscles in Becker muscular dystrophy (BMD) by applying a stepwise approach based …

Becker muscular dystrophy is caused by mutations in the DMD gene that permit significant
residual dystrophin protein expression in patient muscle. This is in contrast to DMD gene …

Background Limb girdle muscular dystrophy type R1/2A (LGMDR1/LGMD2A) is a
progressive myopathy caused by deficiency of calpain 3, a calcium-dependent cysteine …

Objective No treatments are approved for Becker muscular dystrophy (BMD). This study
investigated the efficacy and safety of givinostat, a histone deacetylase pan-inhibitor, in …

Purpose of review The aims of this review are to discuss the imaging modalities used to
assess muscle changes in myopathies, to provide an overview of the inherited myopathies …

Purpose Aim of this study is to compare Quantitative Magnetic Resonance Imaging (qMRI)
measures between Becker Muscular Dystrophy (BMD) and Healthy Subjects (HS) and to …

Introduction Early biomarker discovery studies have praised the value of their emerging
results, predicting an unprecedented impact on health care. Biomarkers are expected to …

Abstract Introduction/Aims Becker muscular dystrophy (BMD) is characterized by variable
disease severity and progression, prompting the identification of biomarkers for clinical trials …