Obesity cardiomyopathy: evidence, mechanisms, and therapeutic implications
The prevalence of heart failure is on the rise and imposes a major health threat, in part, due
to the rapidly increased prevalence of overweight and obesity. To this point …
to the rapidly increased prevalence of overweight and obesity. To this point …
Mitochondrial quality control mechanisms as therapeutic targets in doxorubicin-induced cardiotoxicity
Doxorubicin (DOX) is a chemotherapeutic drug that is utilized for solid tumors and
hematologic malignancies, but its clinical application is hampered by life-threatening …
hematologic malignancies, but its clinical application is hampered by life-threatening …
Mitophagy in cardiovascular diseases: molecular mechanisms, pathogenesis, and treatment
With the growing prevalence of cardiovascular disease (CVD), there is an urgent need to
explore non-conventional therapeutic measures to alleviate the burden of CVD on global …
explore non-conventional therapeutic measures to alleviate the burden of CVD on global …
Protective effects of estrogen on cardiovascular disease mediated by oxidative stress
D Xiang, Y Liu, S Zhou, E Zhou… - Oxidative medicine and …, 2021 - Wiley Online Library
Perimenopause is an important stage of female senescence. Epidemiological investigation
has shown that the incidence of cardiovascular disease in premenopausal women is lower …
has shown that the incidence of cardiovascular disease in premenopausal women is lower …
The Drp1-mediated mitochondrial fission protein interactome as an emerging core player in mitochondrial dynamics and cardiovascular disease therapy
Mitochondria, the membrane-bound cell organelles that supply most of the energy needed
for cell function, are highly regulated, dynamic organelles bearing the ability to alter both …
for cell function, are highly regulated, dynamic organelles bearing the ability to alter both …
Mitochondrial ROS‐Modulated mtDNA: a potential target for cardiac aging
Y Quan, Y Xin, G Tian, J Zhou… - Oxidative medicine and …, 2020 - Wiley Online Library
Mitochondrial DNA (mtDNA) damage is associated with the development of cardiovascular
diseases. Cardiac aging plays a central role in cardiovascular diseases. There is …
diseases. Cardiac aging plays a central role in cardiovascular diseases. There is …
Role of mitochondria in physiology of chondrocytes and diseases of osteoarthritis and rheumatoid arthritis
S Kan, M Duan, Y Liu, C Wang, J Xie - Cartilage, 2021 - journals.sagepub.com
Purpose of Review Mitochondria are recognized to be one of the most important organelles
in chondrocytes for their role in triphosphate (ATP) generation through aerobic …
in chondrocytes for their role in triphosphate (ATP) generation through aerobic …
Mitochondrial heterogeneity in diseases
L Chen, M Zhou, H Li, D Liu, P Liao, Y Zong… - … and Targeted Therapy, 2023 - nature.com
As key organelles involved in cellular metabolism, mitochondria frequently undergo
adaptive changes in morphology, components and functions in response to various …
adaptive changes in morphology, components and functions in response to various …
Mitophagy in cerebral ischemia and ischemia/reperfusion injury
L Shen, Q Gan, Y Yang, C Reis, Z Zhang… - Frontiers in Aging …, 2021 - frontiersin.org
Ischemic stroke is a severe cerebrovascular disease with high mortality and morbidity. In
recent years, reperfusion treatments based on thrombolytic and thrombectomy are major …
recent years, reperfusion treatments based on thrombolytic and thrombectomy are major …
Physical exercise and selective autophagy: benefit and risk on cardiovascular health
Physical exercise promotes cardiorespiratory fitness, and is considered the mainstream of
non-pharmacological therapies along with lifestyle modification for various chronic diseases …
non-pharmacological therapies along with lifestyle modification for various chronic diseases …