Phenotype overlap in the natural history of asthma

FLM Ricciardolo, G Guida, F Bertolini… - European …, 2023 - Eur Respiratory Soc
The heterogeneity of asthma makes it challenging to unravel the pathophysiologic
mechanisms of the disease. Despite the wealth of research identifying diverse phenotypes …

Mitochondrial dysfunction in chronic respiratory diseases: implications for the pathogenesis and potential therapeutics

W Zhou, J Qu, S Xie, Y Sun… - Oxidative Medicine and …, 2021 - Wiley Online Library
Mitochondria are indispensable for energy metabolism and cell signaling. Mitochondrial
homeostasis is sustained with stabilization of mitochondrial membrane potential, balance of …

Global trends in the incidence and mortality of asthma from 1990 to 2019: An age-period-cohort analysis using the global burden of disease study 2019

Y Cao, S Chen, X Chen, W Zou, Z Liu, Y Wu… - Frontiers in Public …, 2022 - frontiersin.org
Background Asthma is a major global health challenge. The global strategic management
and prevention of asthma report has been published, but health system planning for asthma …

Sex, cells, and asthma

SE Chiarella, JC Cardet, YS Prakash - Mayo Clinic Proceedings, 2021 - Elsevier
There are marked sex differences in asthma prevalence and severity. Sex hormones play a
central role in these sex biases and directly interact with multiple key cells involved in the …

Asthma care in the elderly: Practical guidance and challenges for clinical management-a framework of 5 “Ps”

JK Khosa, S Louie, P Lobo Moreno… - Journal of asthma …, 2023 - Taylor & Francis
Uncontrolled asthma in the elderly is a public health issue recognized in developed
countries such as the United States and among the European Union, both from patient …

Ginsenoside Rh1 attenuates ovalbumin-induced asthma by regulating Th1/Th2 cytokines balance

Q Li, C Zhai, G Wang, J Zhou, W Li… - Bioscience …, 2021 - academic.oup.com
ABSTRACT Ginsenoside Rh1 (Rh1) has anti-inflammatory effects in asthma mice, but the
underlying mechanism remains unclear. BALB/c mice were sensitized and challenged with …

Vitamin D status and asthma, lung function, and hospitalization among British adults

Y Zhu, D Jing, H Liang, D Li, Q Chang, M Shen… - Frontiers in …, 2022 - frontiersin.org
Background Vitamin D has been known to be associated with asthma. However, the
association between vitamin D status and asthma, lung function as well as hospitalization …

Asthma prevalence and phenotyping in the general population: the LEAD (lung, hEart, sociAl, boDy) study

C Schiffers, EFM Wouters… - Journal of Asthma …, 2023 - Taylor & Francis
Background Asthma is a chronic heterogeneous respiratory disease involving differential
pathophysiological pathways and consequently distinct asthma phenotypes. Objective and …

Characterisation of the Australian adult population living with Asthma: severe-exacerbation frequency, long-term OCS use and adverse effects

KL Hancock, S Bosnic-Anticevich… - Pragmatic and …, 2022 - Taylor & Francis
Introduction Asthma poses a significant burden for the Australian population. Understanding
severe exacerbation rates, and steroid-related burden for adults diagnosed with asthma …

Human health effects of chronic cadmium exposure

N Zuhra, T Akhtar, R Yasin, I Ghafoor, M Asad… - Cadmium toxicity …, 2024 - Springer
Cadmium (Cd) is a hazardous unnecessary transition metal that is harmful to people and
animals. Cadmium is naturally prevalent in the environment and is frequently obtained from …