Sinomenium acutum: A review of chemistry, pharmacology, pharmacokinetics, and clinical use

XX Zhao, C Peng, H Zhang, LP Qin - Pharmaceutical Biology, 2012 - Taylor & Francis
Context: Sinomenium acutum (Thumb.) Rehd. et Wils.(Menispermaceae, SA) has been used
as a traditional Chinese medicine in the treatment of various diseases for hundreds of years; …

Bioactivities and Mechanisms of Action of Sinomenine and Its Derivatives: A Comprehensive Review

W Hou, L Huang, H Huang, S Liu, W Dai, J Tang… - Molecules, 2024 - mdpi.com
Sinomenine, an isoquinoline alkaloid extracted from the roots and stems of Sinomenium
acutum, has been extensively studied for its derivatives as bioactive agents. This review …

Rapid profiling of alkaloid analogues in Sinomenii Caulis by an integrated characterization strategy and quantitative analysis

ZM Jiang, L Wang, H Pang, Y Guo, PT Xiao… - … of Pharmaceutical and …, 2019 - Elsevier
Alkaloids, the principal constituents in the caulis of Sinomenium acutum, have gained an
increasing interest over the past decades since they are widely employed as a clinical …

Cytotoxic activities of alkaloid constituents from the climbing stems and rhizomes of Sinomenium acutum against cancer stem cells

M Okayama, T Matsumoto, T Kitagawa… - Journal of Natural …, 2024 - Springer
From the methanolic extract of the climbing stems and rhizomes of Sinomenium acutum, two
new aporphine analogues, acutumalkaloids I and II, were isolated together with fifteen …

Comparative Pharmacokinetics Study of Sinomenine in Rats after Oral Administration of Sinomenine Monomer and Sinomenium Acutum Extract

MF Zhang, Y Zhao, KY Jiang, L Han, XY Lu, X Wang… - Molecules, 2014 - mdpi.com
Various products containing sinomenine monomer and extracts of Sinomenium acutum
have been widely applied in clinical treatments. The goal of the present study was to …

New alkaloids and cytotoxic principles from Sinomenium acutum

JJ Cheng, TH Tsai, LC Lin - Planta medica, 2012 - thieme-connect.com
Two new alkaloids, 2-demethyl-oxypalmatine (1) and 5-ethoxycarbonylsinoracutine (2),
were isolated from the rhizomes of Sinomenium acutum, along with thirty-four known …

[PDF][PDF] 青风藤, 青藤碱及其相关制剂的研究进展

王玺, 张智勇, 仇萍, 彭晓珊, 李正… - 中国药学 …, 2021 - journal11.magtechjournal.com
青风藤作为传统中药治疗风湿痹病历史悠久, 其中所含的青藤碱是祛风止痛的主要成分.
现代药理研究表明, 青藤碱具有良好的抗炎, 镇痛, 免疫抑制, 戒毒等作用, 对于类风湿性关节炎 …

Morphinan alkaloids from the leaves of Alphonsea cylindrica and their antibacterial properties

KH Cho, SP Tan, HY Tan, SY Liew, MA Nafiah - Planta Medica, 2023 - thieme-connect.com
A phytochemical study has been carried out on CH 2 Cl 2 extract of Alphonsea cylindrica
leaves, resulting in the isolation of three new morphinan alkaloids. They are kinomenine (1) …

Liquid Chromatography Coupled with Linear Ion Trap Hybrid OrbitrapMass Spectrometry for Determination of Alkaloids in Sinomeniumacutum

J Shan, X Zhao, C Shen, J Ji, J Xu, S Wang, T Xie… - Molecules, 2018 - mdpi.com
The characterization of alkaloids is challenging because of the diversity of structures and the
complicated fragmentation of collision induced structural dissociation in mass spectrometry …

[PDF][PDF] 青风藤总生物碱提取工艺及抗痛风作用

曹沛莹, 陈维佳, 宗颖, 时坤, 李建明, 何忠梅… - 吉林农业大学 …, 2024 - xuebao.jlau.edu.cn
以比色法测得的青藤碱含量为评价指标, 采用乙醇加热回流提取法, 考察乙醇浓度, 液料比,
提取时间和提取次数对青风藤生物碱得率的影响, 用星点设计-响应面法分析从青风藤中提取青 …