Lobular carcinoma in situ (LCIS) is a risk factor and a nonobligate precursor of breast
carcinoma. The relative risk of invasive carcinoma after classic LCIS diagnosis is …

High-risk breast lesions, which comprise benign lesions and in situ carcinomas (lobular
carcinoma in situ and ductal carcinoma in situ), are clinically, morphologically, and …

The NCCN Guidelines for Breast Cancer Screening and Diagnosis have been developed to
facilitate clinical decision making. This manuscript discusses the diagnostic evaluation of …

Breast lesions with uncertain malignant behavior, also known as high-risk or B3 lesions, are
composed of a variety of pathologies with differing risks of associated malignancy. While …

BACKGROUND: No consensus exists on the need to excise breast lesions that yield classic
lobular carcinoma in situ (LCIS) or atypical lobular hyperplasia (ALH)(known together as …

Imaging abnormalities detected by mammographic screening often lead to diagnostic
evaluations, with suspicious abnormalities subjected to image-guided core needle biopsy …

Background Pleomorphic lobular carcinoma in situ (PLCIS) is an unusual variant of LCIS for
which optimal management remains unclear. Methods We conducted a 15-year (2000 …

Optimal management of high-risk breast lesions detected by mammogram yielding atypical
ductal hyperplasia, flat epithelial atypia, atypical lobular hyperplasia, lobular carcinoma in …

Background Lobular neoplasia (LN) represents a spectrum of atypical proliferative lesions,
including atypical lobular hyperplasia and lobular carcinoma-in-situ. The need for excision …

Background Lobular neoplasia (LN) includes atypical lobular hyperplasia (ALH) and lobular
carcinoma in situ (LCIS). LN often is an incidental finding on breast core needle biopsy …