Factor XI inhibitors: cardiovascular perspectives

R De Caterina, D Prisco… - European Heart …, 2023 - academic.oup.com
Anticoagulants are the cornerstone for prevention and treatment of thrombosis but are not
completely effective, and concerns about the risk of bleeding continue to limit their uptake …

[HTML][HTML] Anticoagulation in patients with kidney failure on dialysis: factor XI as a therapeutic target

J Eikelboom, J Floege, R Thadhani, JI Weitz… - Kidney international, 2021 - Elsevier
Chronic kidney disease is present in almost 10% of the world population and is associated
with excess mortality and morbidity. Reduced glomerular filtration rate and the presence and …

[HTML][HTML] An update on the global use of risk assessment models and thromboprophylaxis in hospitalized patients with medical illnesses from the world thrombosis day …

G Forgo, E Micieli, W Ageno, LA Castellucci… - Journal of Thrombosis …, 2022 - Elsevier
Introduction Venous thromboembolism (VTE) is a leading cause of cardiovascular morbidity
and mortality. The majority of VTE events are hospital‐associated. In 2008, the …

[HTML][HTML] Incidence and determinants of thrombotic and bleeding complications in patients with glioblastoma

FHJ Kaptein, MAM Stals, MY Kapteijn… - Journal of Thrombosis …, 2022 - Elsevier
Background Glioblastoma patients are considered to be at high risk of venous
thromboembolism (VTE) and major bleeding (MB), although reliable incidence estimates are …

Anticoagulation in chronic kidney disease: current status and future perspectives

A Jones, D Swan, T Lisman, GD Barnes… - Journal of Thrombosis and …, 2023 - Elsevier
Chronic kidney disease (CKD) is being diagnosed increasingly worldwide. It is often
identified in individuals with co-morbidities, which may increase the already heightened risk …

Anticoagulants for atrial fibrillation: from warfarin and DOACs to the promise of factor XI inhibitors

V Kumar, L Ilkhanoff - Frontiers in Cardiovascular Medicine, 2024 - frontiersin.org
Anticoagulation is the mainstay of stroke prevention in appropriate patients with atrial
fibrillation. Due to advances in pharmacotherapy the anticoagulants used for this purpose …

Substituent effects of sulfonamide derivatives of metformin that can dually improve cellular glucose utilization and anti-coagulation

A Zajda, J Sikora, M Hynninen, J Tampio… - Chemico-Biological …, 2023 - Elsevier
Metformin, the most frequently prescribed medicine for the management of type 2 diabetes,
has been shown to reduce cardiovascular events in diabetic patients in pre-clinical and …

Controversies in the Management of Antiphospholipid Syndrome

SV Porta, DCO de Andrade, D Erkan… - JCR: Journal of …, 2023 - journals.lww.com
Strategies to prevent thrombosis in antiphospholipid antibody (aPL)–positive patients are of
the utmost importance. The risk of thrombosis in patients with aPLs varies, depending on …

Anticoagulants: dose control methods and inhibitors

VO Bitsadze, EV Slukhanchuk, JK Khizroeva… - Obstetrics, Gynecology …, 2022 - gynecology.su
These days, anticoagulants are in great demand. They are used as a prophylaxis for
thromboembolic complications in various diseases and conditions in general therapeutic …

[HTML][HTML] Антикоагулянты: методы контроля дозы и ингибиторы

ВО Бицадзе, ЕВ Слуханчук, ДХ Хизроева… - Акушерство …, 2022 - cyberleninka.ru
Антикоагулянты-крайне востребованные препараты в наши дни. Они используются в
качестве профилактики тромбоэмболических осложнений при различных …