The question of whether human tumors express antigens that can be recognized by the
immune system has been answered with a resounding YES. Most were identified through …

Increasing evidence has linked the humoral immune response with the development of
various cancers. Therefore, there is growing interest in investigating the predictive value of …

Background. The majority of primary liver cancers in adults worldwide are hepatocellular
carcinomas (HCCs, or hepatomas). Thus, a deep understanding of the underlying …

The aim of the present study was to investigate the role and potential regulatory
mechanisms of cyclin B1 (CCNB1) in the proliferation, apoptosis and epithelial‑to …

Cyclin B1 is a key mitotic cyclin in the G2-M phase transition of the cell cycle and is
overexpressed in various malignant tumors. Numerous studies have reported contradictory …

Lung adenocarcinoma (LUAD) accounts for the majority of cancer-related deaths worldwide.
Our study identified key LUAD genes and their potential mechanism via bioinformatics …

Background The primary source of death in the world is non-small cell lung cancer
(NSCLC). However, NSCLCs pathophysiology is still not completely understood. The current …

Abstract Cyclin B1 (CCNB1) is considered as a potential target for a cancer vaccine, as it is
overexpressed in many malignant cells, while being transiently expressed in normal cells …

Curcumin can be used to prevent and treat cancer. However, its exact underlying molecular
mechanisms remain poorly understood. Cathepsin L, a lysosomal cysteine protease, is …

NV669 is an aminosterol derived from squalamine found to possess strong anticancer
effects. The aim of this study was to investigate NV669's beneficial effects on human …