Cesarean myomectomy trends and controversies: an appraisal

R Sparić, A Malvasi, S Kadija, I Babović… - The Journal of …, 2017 - Taylor & Francis
Objective: Although the first report on cesarean myomectomy (CM) was a century ago, the
management of a myomectomy during a cesarean section (CS) remains controversial. The …

[HTML][HTML] Tryptophan catabolism is dysregulated in leiomyomas

TD Chuang, D Quintanilla, D Boos, O Khorram - Fertility and sterility, 2021 - Elsevier
Objective To determine the expression and functional roles of indoleamine 2, 3-dioxygenase
1 (IDO1) and tryptophan 2, 3-dioxygenase (TDO2) in leiomyoma. Design Experimental …

Long-term health-related quality of life and symptom severity following hysterectomy, myomectomy, or uterine artery embolization for the treatment of symptomatic …

RM Anchan, JB Spies, S Zhang, D Wojdyla… - American journal of …, 2023 - Elsevier
Background Few studies have directly compared different surgical procedures for uterine
fibroids with respect to long-term health-related quality of life outcomes and symptom …

Therapeutic effects of long-term administration of tranilast in an animal model for the treatment of fibroids

TD Chuang, L Munoz, D Quintanilla, D Boos… - International journal of …, 2023 - mdpi.com
Tranilast (N-3, 4-dimethoxycinnamoyl anthranilic acid) is an orally administered drug with
antiallergic properties and approved in Japan and the Republic of Korea for the treatment of …

The impact of hormonal replacement treatment in postmenopausal women with uterine fibroids: a state-of-the-art review of the literature

E Moro, E Degli Esposti, G Borghese, F Manzara… - Medicina, 2019 - mdpi.com
Background and Objectives: Hormonal replacement therapy (HRT) is effective in treating
many debilitating symptoms of menopause. However, its use in women with uterine fibroids …

Symptoms of uterine myomas: data of an epidemiological study in Germany

D Foth, FW Röhl, C Friedrich, H Tylkoski… - Archives of gynecology …, 2017 - Springer
Purpose Currently, no reliable data are available concerning the type and frequency of
symptoms in premenopausal women with uterine myomas. Methods 2296 women were …

Expression profiling of lncRNAs, miRNAs, and mRNAs and their differential expression in leiomyoma using next-generation RNA sequencing

TD Chuang, O Khorram - Reproductive Sciences, 2018 - journals.sagepub.com
The objective of this study was to identify the expression profile of long noncoding RNAs
(lncRNAs) with concurrent assessment of microRNA (miRNA) and messenger RNA (mRNA) …

Regulation of cell cycle regulatory proteins by microRNAs in uterine leiomyoma

TD Chuang, O Khorram - Reproductive Sciences, 2019 - journals.sagepub.com
The objective of this study was to determine whether miR-93, miR-29c, and miR-200c, which
we previously reported to be downregulated in leiomyomas, target cell cycle regulatory …

Role of DNA damage and repair mechanisms in uterine fibroid/leiomyomas: a review

SM Toprani, V Kelkar Mane - Biology of Reproduction, 2021 - academic.oup.com
There has been a significant annual increase in the number of cases of uterine leiomyomas
or fibroids (UF) among women of all races and ages across the world. A fortune is usually …

Structural gynecological disease: fibroids, endometriosis, ovarian cysts

AH Farkas, H Abumusa, B Rossiter - Medical Clinics, 2023 - medical.theclinics.com
Benign structural gynecological disease including fibroids, endometriosis, and ovarian cysts
are common pathologic conditions particularly among reproductive-aged women. These …