[HTML][HTML] Mechanisms underlying aberrant expression of miR-29c in uterine leiomyoma
Objective To determine the expression of miR-29c and its target genes in leiomyoma and
the role of NF-κB, specific protein 1 (SP1), and DNA methylation in its regulation. Design …
the role of NF-κB, specific protein 1 (SP1), and DNA methylation in its regulation. Design …
Effect of myomectomy on endometrial cavity: A prospective study of 51 cases
S Bhandari, I Ganguly, P Agarwal… - Journal of human …, 2016 - journals.lww.com
AIMS: Evaluate the incidence of intrauterine adhesion formation after myomectomy and to
identify the associated factors. MATERIALS AND METHODS: In this prospective …
identify the associated factors. MATERIALS AND METHODS: In this prospective …
Tranilast inhibits genes functionally involved in cell proliferation, fibrosis, and epigenetic regulation and epigenetically induces miR-29c expression in leiomyoma cells
Tranilast (N-3, 4-dimethoxycinnamoyl anthranilic acid) is an antiallergic agent with inhibitory
effects on cell proliferation and extracellular matrix production. Here we assess the effect of …
effects on cell proliferation and extracellular matrix production. Here we assess the effect of …
Breast cancer and menopausal hormone therapy by race/ethnicity and body mass index
RT Chlebowski, GL Anderson… - Journal of the …, 2016 - academic.oup.com
In analyses combining estrogen with or without progestin, some observational studies
describe minimal breast cancer risk in obese and black women. Therefore, we examined …
describe minimal breast cancer risk in obese and black women. Therefore, we examined …
Epigenetic regulation in uterine fibroids—the role of ten-eleven translocation enzymes and their potential therapeutic application
M Włodarczyk, G Nowicka, M Ciebiera, M Ali… - International Journal of …, 2022 - mdpi.com
Uterine fibroids (UFs) are monoclonal, benign tumors that contain abnormal smooth muscle
cells and the accumulation of extracellular matrix (ECM). Although benign, UFs are a major …
cells and the accumulation of extracellular matrix (ECM). Although benign, UFs are a major …
Use of depot medroxyprogesterone acetate and prevalent leiomyoma in young African American women
QE Harmon, DD Baird - Human reproduction, 2015 - academic.oup.com
STUDY QUESTION Is use of depot medroxyprogesterone acetate (DMPA) a risk factor for or
a protective factor against prevalent uterine leiomyoma? SUMMARY ANSWER Ever use of …
a protective factor against prevalent uterine leiomyoma? SUMMARY ANSWER Ever use of …
[HTML][HTML] Tranilast induces MiR-200c expression through blockade of RelA/p65 activity in leiomyoma smooth muscle cells
Objective To determine the mechanism by which tranilast induces miR-200c expression in
leiomyoma smooth muscle cells (LSMCs). Design Experimental study. Setting Academic …
leiomyoma smooth muscle cells (LSMCs). Design Experimental study. Setting Academic …
Menopausal hormone therapy and breast cancer mortality: clinical implications
RT Chlebowski, GL Anderson - Therapeutic advances in …, 2015 - journals.sagepub.com
The Women's Health Initiative (WHI) has conducted two randomized, placebo-controlled
clinical trials to evaluate the influence of menopausal hormone therapy on chronic disease …
clinical trials to evaluate the influence of menopausal hormone therapy on chronic disease …
[HTML][HTML] Current understanding of somatic stem cells in leiomyoma formation
Objective To provide a detailed summary of current scientific knowledge of somatic stem
cells (SSCs) in murine and human myometrium and their putative implication in leiomyoma …
cells (SSCs) in murine and human myometrium and their putative implication in leiomyoma …
Next-generation sequencing reveals differentially expressed small noncoding RNAs in uterine leiomyoma
Objective To determine the expression profile of small noncoding RNAs (sncRNAs) in
leiomyoma, which has not been investigated to date. Design Laboratory-based …
leiomyoma, which has not been investigated to date. Design Laboratory-based …