DNA methylation and obesity traits: An epigenome-wide association study. The REGICOR study
S Sayols-Baixeras, I Subirana, A Fernández-Sanlés… - Epigenetics, 2017 - Taylor & Francis
Obesity is associated with increased risk of several diseases and has become epidemic.
Obesity is highly heritable but the genetic variants identified by genome-wide association …
Obesity is highly heritable but the genetic variants identified by genome-wide association …
[HTML][HTML] Carbohydrate and fat intake associated with risk of metabolic diseases through epigenetics of CPT1A
CQ Lai, LD Parnell, CE Smith, T Guo… - The American journal of …, 2020 - Elsevier
Background Epigenome-wide association studies identified the cg00574958 DNA
methylation site at the carnitine palmitoyltransferase-1A (CPT1A) gene to be associated with …
methylation site at the carnitine palmitoyltransferase-1A (CPT1A) gene to be associated with …
Epigenome-wide change and variation in DNA methylation in childhood: trajectories from birth to late adolescence
DNA methylation (DNAm) is known to play a pivotal role in childhood health and
development, but a comprehensive characterization of genome-wide DNAm trajectories …
development, but a comprehensive characterization of genome-wide DNAm trajectories …
[HTML][HTML] Epigenetic associations of type 2 diabetes and BMI in an Arab population
WA Al Muftah, M Al-Shafai, SB Zaghlool, A Visconti… - Clinical …, 2016 - Springer
Background The prevalence of type 2 diabetes (T2D) and obesity has dramatically
increased within a few generations, reaching epidemic levels. In addition to genetic risk …
increased within a few generations, reaching epidemic levels. In addition to genetic risk …
A biosocial return to race? A cautionary view for the postgenomic era
Recent studies demonstrating epigenetic and developmental sensitivity to early
environments, as exemplified by fields like the Developmental Origins of Health and …
environments, as exemplified by fields like the Developmental Origins of Health and …
Analysis of blood methylation quantitative trait loci in East Asians reveals ancestry-specific impacts on complex traits
Methylation quantitative trait loci (mQTLs) are essential for understanding the role of DNA
methylation changes in genetic predisposition, yet they have not been fully characterized in …
methylation changes in genetic predisposition, yet they have not been fully characterized in …
[HTML][HTML] Epigenome-wide association study (EWAS) on lipids: the Rotterdam Study
Background DNA methylation is a key epigenetic mechanism that is suggested to be
associated with blood lipid levels. We aimed to identify CpG sites at which DNA methylation …
associated with blood lipid levels. We aimed to identify CpG sites at which DNA methylation …
Epigenetic reprogramming in metabolic disorders: nutritional factors and beyond
Z Cheng, L Zheng, FA Almeida - The Journal of nutritional biochemistry, 2018 - Elsevier
Environmental factors (eg, malnutrition and physical inactivity) contribute largely to
metabolic disorders including obesity, type 2 diabetes, cardiometabolic disease and …
metabolic disorders including obesity, type 2 diabetes, cardiometabolic disease and …
Epigenetic patterns in blood associated with lipid traits predict incident coronary heart disease events and are enriched for results from genome-wide association …
Background—Genome-wide association studies have identified loci influencing circulating
lipid concentrations in humans; further information on novel contributing genes, pathways …
lipid concentrations in humans; further information on novel contributing genes, pathways …
The potential of DNA methylation as a biomarker for obesity and smoking
A Heikkinen, S Bollepalli… - Journal of internal …, 2022 - Wiley Online Library
DNA methylation is an epigenetic modification that has consistently been shown to be linked
with a variety of human traits and diseases. Because DNA methylation is dynamic and …
with a variety of human traits and diseases. Because DNA methylation is dynamic and …