An epigenome-wide association study meta-analysis of educational attainment
The epigenome is associated with biological factors, such as disease status, and
environmental factors, such as smoking, alcohol consumption and body mass index …
environmental factors, such as smoking, alcohol consumption and body mass index …
[HTML][HTML] Effect of prenatal bisphenol A exposure on early childhood body mass index through epigenetic influence on the insulin-like growth factor 2 receptor (IGF2R) …
Objectives Epigenetic mechanisms have been suggested to play a role in the link between
in utero exposure to bisphenol A (BPA) and pediatric obesity; however, there is little …
in utero exposure to bisphenol A (BPA) and pediatric obesity; however, there is little …
Imputation to whole-genome sequence using multiple pig populations and its use in genome-wide association studies
S van den Berg, J Vandenplas, FA van Eeuwijk… - Genetics Selection …, 2019 - Springer
Background Use of whole-genome sequence data (WGS) is expected to improve
identification of quantitative trait loci (QTL). However, this requires imputation to WGS, often …
identification of quantitative trait loci (QTL). However, this requires imputation to WGS, often …
Characterisation of ethnic differences in DNA methylation between UK-resident South Asians and Europeans
HR Elliott, K Burrows, JL Min, T Tillin, D Mason… - Clinical …, 2022 - Springer
Ethnic differences in non-communicable disease risk have been described between
individuals of South Asian and European ethnicity that are only partially explained by …
individuals of South Asian and European ethnicity that are only partially explained by …
Alcohol consumption is associated with widespread changes in blood DNA methylation: analysis of cross‐sectional and longitudinal data
DNA methylation may be one of the mechanisms by which alcohol consumption is
associated with the risk of disease. We conducted a large‐scale, cross‐sectional, genome …
associated with the risk of disease. We conducted a large‐scale, cross‐sectional, genome …
The association of DNA methylation with body mass index: distinguishing between predictors and biomarkers
Background DNA methylation is associated with body mass index (BMI), but it is not clear if
methylation scores are biomarkers for extant BMI or predictive of future BMI. Here, we …
methylation scores are biomarkers for extant BMI or predictive of future BMI. Here, we …
Identification and validation of seven new loci showing differential DNA methylation related to serum lipid profile: an epigenome-wide approach. The REGICOR study
S Sayols-Baixeras, I Subirana… - Human molecular …, 2016 - academic.oup.com
Lipid traits (total, low-density and high-density lipoprotein cholesterol, and triglycerides) are
risk factors for cardiovascular disease. DNA methylation is not only an inherited but also …
risk factors for cardiovascular disease. DNA methylation is not only an inherited but also …
The genomic landscape of African populations in health and disease
CN Rotimi, AR Bentley, AP Doumatey… - Human molecular …, 2017 - academic.oup.com
A deeper appreciation of the complex architecture of African genomes is critical to the global
effort to understand human history, biology and differential distribution of disease by …
effort to understand human history, biology and differential distribution of disease by …
An epigenome-wide association study of obesity-related traits
We conducted an epigenome-wide association study on obesity-related traits. We used data
from 2 prospective, population-based cohort studies: the Rotterdam Study (RS)(2006–2013) …
from 2 prospective, population-based cohort studies: the Rotterdam Study (RS)(2006–2013) …
An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis
Despite existing reports on differential DNA methylation in type 2 diabetes (T2D) and
obesity, our understanding of its functional relevance remains limited. Here we show the …
obesity, our understanding of its functional relevance remains limited. Here we show the …