Epigenetics in precision nutrition

X Li, L Qi - Journal of Personalized Medicine, 2022 - mdpi.com
Precision nutrition is an emerging area of nutrition research, with primary focus on the
individual variability in response to dietary and lifestyle factors, which are mainly determined …

An epigenome-wide association study in whole blood of measures of adiposity among Ghanaians: the RODAM study

KAC Meeks, P Henneman, A Venema, T Burr… - Clinical …, 2017 - Springer
Background Epigenome-wide association studies (EWAS) have identified DNA methylation
loci involved in adiposity. However, EWAS on adiposity in sub-Saharan Africans are lacking …

What role does the endocannabinoid system play in the pathogenesis of obesity?

P Schulz, S Hryhorowicz, AM Rychter, A Zawada… - Nutrients, 2021 - mdpi.com
The endocannabinoid system (ECS) is an endogenous signaling system formed by specific
receptors (cannabinoid type 1 and type 2 (CB1 and CB2)), their endogenous ligands …

Impact of BMI and waist circumference on epigenome-wide DNA methylation and identification of epigenetic biomarkers in blood: an EWAS in multi-ethnic Asian …

Y Chen, I Kassam, SH Lau, JS Kooner, R Wilson… - Clinical …, 2021 - Springer
Background The prevalence of obesity and its related chronic diseases have been
increasing especially in Asian countries. Obesity-related genetic variants have been …

Male obesity effects on sperm and next-generation cord blood DNA methylation

R Potabattula, M Dittrich, M Schorsch, T Hahn, T Haaf… - PloS one, 2019 - journals.plos.org
The prevalence of metabolic disorders, in particular obesity has dramatically increased
worldwide. Genetic variants explain only a minor part of the obesity epidemic induced by …

Insights into the multifactorial causation of obesity by integrated genetic and epigenetic analysis

S Diels, W Vanden Berghe, W Van Hul - Obesity Reviews, 2020 - Wiley Online Library
Obesity is a highly heritable multifactorial disease that places an enormous burden on
human health. Its increasing prevalence and the concomitant‐reduced life expectancy has …

Examining the association between adiposity and DNA methylation: a systematic review and meta‐analysis

WL Do, J Gohar, LE McCullough, KI Galaviz… - Obesity …, 2021 - Wiley Online Library
Obesity is associated with widespread differential DNA methylation (DNAm) patterns, though
there have been limited overlap in the obesity‐associated cytosine–guanine nucleotide pair …

Placental DNA methylation changes associated with maternal prepregnancy BMI and gestational weight gain

D Shrestha, M Ouidir, T Workalemahu, X Zeng… - International Journal of …, 2020 - nature.com
Background Maternal obesity prior to or during pregnancy influences fetal growth,
predisposing the offspring to increased risk for obesity across the life course. Placental …

[HTML][HTML] Epigenetic disturbances in obesity and diabetes: Epidemiological and functional insights

M Loh, L Zhou, HK Ng, JC Chambers - Molecular Metabolism, 2019 - Elsevier
Background Obesity and type 2 diabetes (T2D) are major public health issues worldwide,
and put a significant burden on the healthcare system. Genetic variants, along with …

Genome-wide analysis of DNA methylation and acute coronary syndrome

J Li, X Zhu, K Yu, H Jiang, Y Zhang, S Deng… - Circulation …, 2017 - Am Heart Assoc
Rationale: Acute coronary syndrome (ACS) is a leading cause of death worldwide. Immune
functions play a vital role in ACS development; however, whether epigenetic modulation …