The epidemic of obesity has become pandemic, putting a significant burden on the world's
healthcare system. While the heritability of the disease is high, all the identified genetic …

Introduction: Cardiovascular (CVD) risk assessment with traditional risk factors (age, sex,
blood pressure, lipids, smoking and diabetes) has remained relatively invariant over the past …

Results: Cross-sectional analysis identified 310 CpGs associated with BMI with P< 1.0× 10−
7, 225 of which had not been reported previously. Of these 225 novel associations, 172 …

Background The high prevalence of obesity among US adults has resulted in significant
increases in associated metabolic disorders such as diabetes, dyslipidemia, and high blood …

It remains largely unknown as to why some individuals experience substantial weight loss
with obesity interventions, while others receiving these same interventions do not. Person …

Obesity is a major risk factor for cardiovascular disease. Blood-detected epigenetic profiles
may serve as non-invasive clinically relevant biomarkers. Therefore, we investigated DNA …

Obesity and eating disorders are conditions that involve eating behaviors and are
sometimes comorbid. Current evidence supports alterations in immunoinflammatory …

The current review provides a literature overview of epigenetic modifications in lipid
metabolism and other lipid-related phenotypes and diseases focusing on EWAS of DNA …

Many epigenetic association studies have attempted to identify DNA methylation markers in
blood that are able to mirror those in target tissues. Although some have suggested potential …

The incidence of obesity has dramatically increased over the last decades. Recently, there
has been a growing interest in the possible association between the pandemics of obesity …