Abstract Purpose of Review Enormous progress has been made in understanding the
genetic architecture of obesity and the correlation of epigenetic marks with obesity and …

Chronic stress has a significant impact on obesity. However, how stress influences obesity
remains unclear. We conducted an epigenome-wide DNA methylation association analysis …

Recently, a genome-wide analysis identified DNA methylation of the HIF3A (hypoxia-
inducible factor 3A) as strongest correlate of BMI. Here we tested the hypothesis that HIF3A …

Cardiometabolic diseases include metabolic syndrome, obesity, type 2 diabetes mellitus,
and hypertension. Epigenetic modifications participate in cardiometabolic diseases through …

Obesity affects 600 million people globally and over one third of the American population.
Along with associated comorbidities, including cardiovascular disease, stroke, diabetes, and …

Individual differences in drug response have always existed in clinical treatment. Many non‐
genetic factors show non‐negligible impacts on personalized medicine. Emerging studies …

Obesity is a heritable trait that contributes to substantial global morbidity and mortality. Here,
we summarize findings from the past decade of genetic and epigenetic research focused on …

Results: Four CpG sites reached genome-wide significance (false discovery rate (FDR) q<
0.05) in the discovery set and associations for all four were significant at strict Bonferroni …

Obesity and abdominal obesity have been closely related to cardiovascular outcomes, and
recent evidence has indicated that environmental and genetic factors act in concert in …

Objective To determine if measures of adverse childhood experiences and DNA methylation
relate to indices of obesity in youth. Study design Participants were derived from a cohort of …