The observation that heart failure with reduced ejection fraction is associated with elevated
circulating levels of pro-inflammatory cytokines opened a new area of research that has …

Studies show that the autonomic nervous system (ANS) has an important impact on health in
general. In response to environmental demands, homeostatic processes are often …

Significance: Social and demographic changes have led to an increased prevalence of
loneliness and social isolation in modern society. Recent Advances: Population-based …

The effects of autonomic innervation of tumors on tumor growth remain unclear. Here we
developed a series of genetic techniques to manipulate autonomic innervation in a tumor …

Pain is the major symptom of osteoarthritis (OA) and is an important factor in strategies to
manage this disease. However, the current standard of care does not provide satisfactory …

The inflammatory reflex is known as the body's primary defense against infection and has
been implicated in a number of diseases. The magnitude of the inflammatory response is …

Interactions between the nervous and immune systems were recognized long ago, but
recent studies show that this crosstalk occurs more frequently than was previously …

The autonomic nervous system (ANS) and the immune system are deeply interrelated. The
ANS regulates both innate and adaptive immunity through the sympathetic and …

The nervous system and immune system have broad and overlapping distributions in the
body, and interactions of these ubiquitous systems are central to the field of …

There is growing interest in the complex relationship between the nervous and immune
systems and how its alteration can affect homeostasis and result in the development of …