[HTML][HTML] Modular engineering for microbial production of carotenoids
C Li, CA Swofford, AJ Sinskey - Metabolic Engineering Communications, 2020 - Elsevier
There is an increasing demand for carotenoids due to their applications in the food, flavor,
pharmaceutical and feed industries, however, the extraction and synthesis of these …
pharmaceutical and feed industries, however, the extraction and synthesis of these …
Highly efficient neutralizer-free l-malic acid production using engineered Saccharomyces cerevisiae
L Sun, Q Zhang, X Kong, Y Liu, J Li, G Du, X Lv… - Bioresource …, 2023 - Elsevier
In industrial bioproduction of organic acids, numerous neutralizers are required which
substantially increases production costs and burdens the environment. To address this …
substantially increases production costs and burdens the environment. To address this …
Engineering monoterpene production in yeast using a synthetic dominant negative geranyl diphosphate synthase
Monoterpenes have an established use in the food and cosmetic industries and have
recently also found application as advanced biofuels. Although metabolic engineering …
recently also found application as advanced biofuels. Although metabolic engineering …
Chemicals from lignocellulosic biomass: a critical comparison between biochemical, microwave and thermochemical conversion methods
The past decades have seen an increasing interest in developing pathways to produce bio-
based chemicals from lignocellulosic biomass and organic waste as renewable resources …
based chemicals from lignocellulosic biomass and organic waste as renewable resources …
In vitro reconstitution of mevalonate pathway and targeted engineering of farnesene overproduction in Escherichia coli
Approaches using metabolic engineering and synthetic biology to overproduce terpenoids,
such as the precursors of taxol and artemisinin, in microbial systems have achieved initial …
such as the precursors of taxol and artemisinin, in microbial systems have achieved initial …
Metabolic engineering of plant monoterpenes, sesquiterpenes and diterpenes—current status and future opportunities
Terpenoids (aka isoprenoids) represent the most diverse class of natural products found in
plants, with tens of thousands of reported structures. Plant‐derived terpenoids have a …
plants, with tens of thousands of reported structures. Plant‐derived terpenoids have a …
What makes a P450 tick?
The cytochromes P450 (P450s) are probably nature's most versatile enzymes in terms of
both their vast substrate range and the diverse types of molecular transformations performed …
both their vast substrate range and the diverse types of molecular transformations performed …
[HTML][HTML] Metabolic engineering and synthetic biology for isoprenoid production in Escherichia coli and Saccharomyces cerevisiae
Isoprenoids, often called terpenoids, are the most abundant and highly diverse family of
natural organic compounds. In plants, they play a distinct role in the form of photosynthetic …
natural organic compounds. In plants, they play a distinct role in the form of photosynthetic …
Compartmentalization and transporter engineering strategies for terpenoid synthesis
K Jin, H Xia, Y Liu, J Li, G Du, X Lv, L Liu - Microbial Cell Factories, 2022 - Springer
Microbial cell factories for terpenoid synthesis form a less expensive and more environment-
friendly approach than chemical synthesis and extraction, and are thus being regarded as …
friendly approach than chemical synthesis and extraction, and are thus being regarded as …
Cell-Free Mixing of Escherichia coli Crude Extracts to Prototype and Rationally Engineer High-Titer Mevalonate Synthesis
Cell-free metabolic engineering (CFME) is advancing a powerful paradigm for accelerating
the design and synthesis of biosynthetic pathways. However, as most cell-free biomolecule …
the design and synthesis of biosynthetic pathways. However, as most cell-free biomolecule …