Engineering plant sesquiterpene synthesis into yeasts: a review
J Mai, W Li, R Ledesma-Amaro… - Journal of Agricultural and …, 2021 - ACS Publications
Sesquiterpenes are natural compounds composed of three isoprene units. They represent
the largest class of terpene compounds found in plants, and many have remarkable …
the largest class of terpene compounds found in plants, and many have remarkable …
[HTML][HTML] Fermentative production of Vitamin E tocotrienols in Saccharomyces cerevisiae under cold-shock-triggered temperature control
B Shen, P Zhou, X Jiao, Z Yao, L Ye, H Yu - Nature communications, 2020 - nature.com
The diverse physiological functions of tocotrienols have listed them as valuable
supplementations to α-tocopherol-dominated Vitamin E products. To make tocotrienols more …
supplementations to α-tocopherol-dominated Vitamin E products. To make tocotrienols more …
[HTML][HTML] Microbial utilization of next-generation feedstocks for the biomanufacturing of value-added chemicals and food ingredients
Global shift to sustainability has driven the exploration of alternative feedstocks beyond
sugars for biomanufacturing. Recently, C1 (CO2, CO, methane, formate and methanol) and …
sugars for biomanufacturing. Recently, C1 (CO2, CO, methane, formate and methanol) and …
Metabolic engineering of plant monoterpenes, sesquiterpenes and diterpenes—current status and future opportunities
Terpenoids (aka isoprenoids) represent the most diverse class of natural products found in
plants, with tens of thousands of reported structures. Plant‐derived terpenoids have a …
plants, with tens of thousands of reported structures. Plant‐derived terpenoids have a …
Artemisinin, a miracle of traditional Chinese medicine
LY Kong, RX Tan - Natural Product Reports, 2015 - pubs.rsc.org
The 2015 Nobel Prize in Physiology or Medicine, shared by Professor Youyou Tu, focused
worldwide attention on artemisinin, a natural product antimalarial drug inspired by traditional …
worldwide attention on artemisinin, a natural product antimalarial drug inspired by traditional …
Cell-Free Mixing of Escherichia coli Crude Extracts to Prototype and Rationally Engineer High-Titer Mevalonate Synthesis
Cell-free metabolic engineering (CFME) is advancing a powerful paradigm for accelerating
the design and synthesis of biosynthetic pathways. However, as most cell-free biomolecule …
the design and synthesis of biosynthetic pathways. However, as most cell-free biomolecule …
[HTML][HTML] Orthogonal monoterpenoid biosynthesis in yeast constructed on an isomeric substrate
Synthetic biology efforts for the production of valuable chemicals are frequently hindered by
the structure and regulation of the native metabolic pathways of the chassis. This is …
the structure and regulation of the native metabolic pathways of the chassis. This is …
Biodefense in the age of synthetic biology
National Academies of Sciences, Division on Earth… - 2018 - books.google.com
Scientific advances over the past several decades have accelerated the ability to engineer
existing organisms and to potentially create novel ones not found in nature. Synthetic …
existing organisms and to potentially create novel ones not found in nature. Synthetic …
[HTML][HTML] Producing aglycons of ginsenosides in bakers' yeast
Z Dai, B Wang, Y Liu, M Shi, D Wang, X Zhang, T Liu… - Scientific reports, 2014 - nature.com
Ginsenosides are the primary bioactive components of ginseng, which is a popular
medicinal plant that exhibits diverse pharmacological activities. Protopanaxadiol …
medicinal plant that exhibits diverse pharmacological activities. Protopanaxadiol …
Synthesis of customized petroleum-replica fuel molecules by targeted modification of free fatty acid pools in Escherichia coli
TP Howard, S Middelhaufe, K Moore… - Proceedings of the …, 2013 - National Acad Sciences
Biofuels are the most immediate, practical solution for mitigating dependence on fossil
hydrocarbons, but current biofuels (alcohols and biodiesels) require significant downstream …
hydrocarbons, but current biofuels (alcohols and biodiesels) require significant downstream …