Abstract World Health Organization reports that half of the population in developing
countries are at risk of malaria infection. Artemisinin, the most potent anti-malaria drug, is a …

Covering: up to February, 2018 This review briefly introduces and summarizes current
knowledge about the Clustered Regularly Interspaced Short Palindromic Repeats …

In industrial bioproduction of organic acids, numerous neutralizers are required which
substantially increases production costs and burdens the environment. To address this …

Background Cost-effective production of the highly effective anti-cancer drug, paclitaxel
(Taxol®), remains limited despite growing global demands. Low yields of the critical …

Efficient microbial synthesis of chemicals requires the coordinated supply of precursors and
cofactors to maintain cell growth and product formation. Substrates with different entry points …

Plant natural products (PNPs) are widely used as pharmaceuticals, nutraceuticals,
seasonings, pigments, etc., with a huge commercial value on the global market. However …

Background Sclareol is a diterpene natural product of high value for the fragrance industry.
Its labdane carbon skeleton and its two hydroxyl groups also make it a valued starting …

The past decades have seen an increasing interest in developing pathways to produce bio-
based chemicals from lignocellulosic biomass and organic waste as renewable resources …

Tetrahydropapaverine (THP) and papaverine are plant natural products with clinically
significant roles. THP is a precursor in the production of the drugs atracurium and …

Isoprenoids are diverse natural compounds, which have various applications as
pharmaceuticals, fragrances, and solvents. The low yield of isoprenoids in plants makes …