[HTML][HTML] Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities

G Hajishengallis, T Chavakis - Nature Reviews Immunology, 2021 - nature.com
Periodontitis, a major inflammatory disease of the oral mucosa, is epidemiologically
associated with other chronic inflammation-driven disorders, including cardio-metabolic …

Staging and grading of periodontitis: Framework and proposal of a new classification and case definition

MS Tonetti, H Greenwell… - Journal of …, 2018 - Wiley Online Library
Background Authors were assigned the task to develop case definitions for periodontitis in
the context of the 2017 World Workshop on the Classification of Periodontal and Peri …

Electrochemical methods for the analysis of clinically relevant biomolecules

M Labib, EH Sargent, SO Kelley - Chemical reviews, 2016 - ACS Publications
Rapid progress in identifying biomarkers that are hallmarks of disease has increased
demand for high-performance detection technologies. Implementation of electrochemical …

Causal association between periodontitis and hypertension: evidence from Mendelian randomization and a randomized controlled trial of non-surgical periodontal …

M Czesnikiewicz-Guzik, G Osmenda… - European heart …, 2019 - academic.oup.com
Aims Inflammation is an important driver of hypertension. Periodontitis is a chronic
inflammatory disease, which could provide a mechanism for pro-hypertensive immune …

Periodontal complications of hyperglycemia/diabetes mellitus: epidemiologic complexity and clinical challenge

T Kocher, J König, WS Borgnakke, C Pink… - Periodontology …, 2018 - Wiley Online Library
This report provides a comprehensive overview of the adverse effects of hyperglycemia on
the periodontium. It combines data from literature reviews of original data from two large …

[HTML][HTML] Periodontitis, low-grade inflammation and systemic health: a scoping review

G Cecoro, M Annunziata, MT Iuorio, L Nastri, L Guida - Medicina, 2020 - mdpi.com
Background and objectives: Periodontitis is a multifactorial chronic inflammatory infectious
disease in which an infection is necessary, but not sufficient, for development of the …

Does diabetes increase the risk of periodontitis? A systematic review and meta-regression analysis of longitudinal prospective studies

GG Nascimento, FRM Leite, P Vestergaard, F Scheutz… - Acta …, 2018 - Springer
Aim Even though the association between diabetes and periodontitis is taken for granted,
results on this association are conflicting within the literature. This systematic review …

Periodontitis and metabolic diseases (diabetes and obesity): Tackling multimorbidity

C Marruganti, JE Suvan, F D'Aiuto - Periodontology 2000, 2023 - Wiley Online Library
Noncommunicable diseases (NCDs) are multifactorial, long‐term, chronic conditions that
represent a burden to health‐care systems worldwide as they can only be controlled rather …

Identification of the different salivary Interleukin-6 profiles in patients with periodontitis: a cross-sectional study

G Isola, AL Giudice, A Polizzi, A Alibrandi… - Archives of Oral …, 2021 - Elsevier
Objective The aim of this study was to analyze and identify the association among salivary
interleukin-6 (IL-6) levels and periodontitis (PT) and to determine the significant trend of this …

Association of vitamin D in patients with periodontitis: A cross‐sectional study

G Isola, A Alibrandi, E Rapisarda… - Journal of …, 2020 - Wiley Online Library
Abstract Background and Objective Vitamin D has been considered to possess anti‐
inflammatory and antimicrobial activity, which may be a link for the known interaction of …