Epigenetic regulation in cardiovascular disease: mechanisms and advances in clinical trials
Y Shi, H Zhang, S Huang, L Yin, F Wang… - … and Targeted Therapy, 2022 - nature.com
Epigenetics is closely related to cardiovascular diseases. Genome-wide linkage and
association analyses and candidate gene approaches illustrate the multigenic complexity of …
association analyses and candidate gene approaches illustrate the multigenic complexity of …
CircRNAs: role in human diseases and potential use as biomarkers
L Verduci, E Tarcitano, S Strano, Y Yarden… - Cell death & …, 2021 - nature.com
Circular RNAs (circRNAs) are a class of endogenous RNAs characterized by a covalent
loop structure. In comparison to other types of RNAs, the abundance of circRNAs is relatively …
loop structure. In comparison to other types of RNAs, the abundance of circRNAs is relatively …
Best practice standards for circular RNA research
AF Nielsen, A Bindereif, I Bozzoni, M Hanan… - Nature …, 2022 - nature.com
Circular RNAs (circRNAs) are formed in all domains of life and via different mechanisms.
There has been an explosion in the number of circRNA papers in recent years; however, as …
There has been an explosion in the number of circRNA papers in recent years; however, as …
CircRNAs in cancer metabolism: a review
T Yu, Y Wang, Y Fan, N Fang, T Wang, T Xu… - Journal of hematology & …, 2019 - Springer
Altered energy metabolism is a hallmark of tumors aiming at supplying necessary nutrients
for tumorigenesis and development. These redirected metabolic pathways associated with …
for tumorigenesis and development. These redirected metabolic pathways associated with …
[HTML][HTML] Cardiac telocytes inhibit cardiac microvascular endothelial cell apoptosis through exosomal miRNA-21-5p-targeted cdip1 silencing to improve angiogenesis …
Z Liao, Y Chen, C Duan, K Zhu, R Huang, H Zhao… - Theranostics, 2021 - ncbi.nlm.nih.gov
Promotion of cardiac angiogenesis in ischemic myocardium is a critical strategy for repairing
and regenerating the myocardium after myocardial infarction (MI). Currently, effective …
and regenerating the myocardium after myocardial infarction (MI). Currently, effective …
Circular RNAs: expression, localization, and therapeutic potentials
Circular RNAs (circRNAs) are RNAs with a unique circular structure that is generated from
back-splicing processes. These circular molecules were discovered more than 40 years ago …
back-splicing processes. These circular molecules were discovered more than 40 years ago …
Competing endogenous RNAs, non-coding RNAs and diseases: an intertwined story
U Ala - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs), a class of small non-coding RNA molecules, are responsible for RNA
silencing and post-transcriptional regulation of gene expression. They can mediate a fine …
silencing and post-transcriptional regulation of gene expression. They can mediate a fine …
Circular RNAs: a novel class of functional RNA molecules with a therapeutic perspective
Circular RNAs (circRNAs) are a subclass of non-coding RNAs that lack free 3′ and 5′
ends and, thus, exist as continuous loop RNAs. Such circular transcripts have been …
ends and, thus, exist as continuous loop RNAs. Such circular transcripts have been …
Targeting the highly abundant circular RNA circSlc8a1 in cardiomyocytes attenuates pressure overload induced hypertrophy
TB Lim, E Aliwarga, TDA Luu, YP Li, SL Ng… - Cardiovascular …, 2019 - academic.oup.com
Aims We and others have previously described the expression landscape of circular RNA
(circRNA) in mouse and human hearts. However, the functional relevance of many of these …
(circRNA) in mouse and human hearts. However, the functional relevance of many of these …
[HTML][HTML] CircSV2b participates in oxidative stress regulation through miR-5107-5p-Foxk1-Akt1 axis in Parkinson's disease
Q Cheng, J Wang, M Li, J Fang, H Ding, J Meng… - Redox biology, 2022 - Elsevier
As a novel type of non-coding RNAs, covalently closed circular RNAs (circRNAs) are
ubiquitously expressed in eukaryotes. Emerging studies have indicated that dysregulation of …
ubiquitously expressed in eukaryotes. Emerging studies have indicated that dysregulation of …