Oxidative damage in neurodegeneration: roles in the pathogenesis and progression of Alzheimer disease
M Perluigi, F Di Domenico… - Physiological …, 2024 - journals.physiology.org
Alzheimer disease (AD) is associated with multiple etiologies and pathological mechanisms,
among which oxidative stress (OS) appears as a major determinant. Intriguingly, OS arises …
among which oxidative stress (OS) appears as a major determinant. Intriguingly, OS arises …
Dietary sources, health benefits, and risks of caffeine
A Saimaiti, DD Zhou, J Li, RG Xiong… - Critical Reviews in …, 2023 - Taylor & Francis
Dietary intake of caffeine has significantly increased in recent years, and beneficial and
harmful effects of caffeine have been extensively studied. This paper reviews antioxidant …
harmful effects of caffeine have been extensively studied. This paper reviews antioxidant …
Pharmacology of adenosine receptors: Recent advancements
F Vincenzi, S Pasquini, C Contri, M Cappello, M Nigro… - Biomolecules, 2023 - mdpi.com
Adenosine receptors (ARs) are widely acknowledged pharmacological targets yet are still
underutilized in clinical practice. Their ubiquitous distribution in almost all cells and tissues …
underutilized in clinical practice. Their ubiquitous distribution in almost all cells and tissues …
[HTML][HTML] Amyloid Precursor Protein: A Regulatory Hub in Alzheimer's Disease
J Chen, JS Chen, S Li, F Zhang, J Deng… - Aging and …, 2024 - ncbi.nlm.nih.gov
Decades of research have demonstrated an incontrovertible role of amyloid-β (Aβ) in the
etiology of Alzheimer's disease (AD). However, the overemphasis on the pathological …
etiology of Alzheimer's disease (AD). However, the overemphasis on the pathological …
Therapeutic considerations of bioactive compounds in Alzheimer's disease and Parkinson's disease: Dissecting the molecular pathways
BC Phukan, R Roy, I Gahatraj… - Phytotherapy …, 2023 - Wiley Online Library
Leading neurodegenerative diseases Alzheimer's disease (AD) and Parkinson's disease
(PD) are characterized by the impairment of memory and motor functions, respectively …
(PD) are characterized by the impairment of memory and motor functions, respectively …
Dexmedetomidine improves the circulatory dysfunction of the glymphatic system induced by sevoflurane through the PI3K/AKT/ΔFosB/AQP4 pathway in young mice
S Wang, X Yu, L Cheng, W Ren, G Wen, X Wu… - Cell Death & …, 2024 - nature.com
Multiple sevoflurane exposures may damage the developing brain. The neuroprotective
function of dexmedetomidine has been widely confirmed in animal experiments and human …
function of dexmedetomidine has been widely confirmed in animal experiments and human …
Caffeine restores neuronal damage and inflammatory response in a model of intraventricular hemorrhage of the preterm newborn
P Alves-Martinez, I Atienza-Navarro… - Frontiers in Cell and …, 2022 - frontiersin.org
Germinal matrix-intraventricular hemorrhage (GM-IVH) is the most frequent intracranial
hemorrhage in the preterm infant (PT). Long-term GM-IVH-associated sequelae include …
hemorrhage in the preterm infant (PT). Long-term GM-IVH-associated sequelae include …
Caffeine Improve Memory and Cognition via Modulating Neural Progenitor Cell Survival and Decreasing Oxidative Stress in Alzheimer's Rat Model
Aims: Caffeine possesses potent antioxidant, anti-inflammatory and anti-apoptotic activities
against a variety of neurodegenerative diseases, including Alzheimer's disease (AD) and …
against a variety of neurodegenerative diseases, including Alzheimer's disease (AD) and …
Dynamic Regulation of Mitochondrial [Ca2+] in Hippocampal Neurons
While neuronal mitochondria have been studied extensively in their role in health and
disease, the rules that govern calcium regulation in mitochondria remain somewhat vague …
disease, the rules that govern calcium regulation in mitochondria remain somewhat vague …
A combination of caffeine supplementation and enriched environment in an Alzheimer's disease mouse model
M Stazi, S Zampar, HW Klafki, T Meyer… - International Journal of …, 2023 - mdpi.com
A variety of factors has been associated with healthy brain aging, and epidemiological
studies suggest that physical activity and nutritional supplements such as caffeine may …
studies suggest that physical activity and nutritional supplements such as caffeine may …