Mitochondrial permeability transition (mPT) is a phenomenon that abruptly causes the flux of
low molecular weight solutes (molecular weight up to 1,500) across the generally …

Neuronal cell death occurs extensively during development and pathology, where it is
especially important because of the limited capacity of adult neurons to proliferate or be …

Hypoxic–ischemic encephalopathy, also referred as HIE, is a type of brain injury or damage
that is caused by a lack of oxygen to the brain during neonatal period. The incidence is …

The susceptibility of the brain to ischaemic injury dramatically limits its viability following
interruptions in blood flow. However, data from studies of dissociated cells, tissue …

Given the increasing incidence and prevalence of skin cancer, dermatologists are more
frequently recommending sunscreens to their patients. However, the safety of titanium …

Mitochondrial permeability transition (MPT) is the sudden loss in the permeability of the
inner mitochondrial membrane (IMM) to low-molecular-weight solutes. Due to osmotic …

Mitochondria play a central role in cell life and cell death. An increasing number of studies
place mitochondrial dysfunction at the heart of disease, most notably in the heart and the …

Recent research has shown the essential role of reduced blood flow and free radical
formation in the cochlea in noise-induced hearing loss (NIHL). The amount, distribution, and …

Activation of glutamate receptors can trigger the death of neurons and some types of glial
cells, particularly when the cells are coincidentally subjected to adverse conditions such as …

Calpain is a ubiquitous calcium-sensitive protease that is essential for normal physiologic
neuronal function. However, alterations in calcium homeostasis lead to persistent …