By eliciting distinct transcriptional responses, the oestrogen receptors (ERs) ERα and ERβ
exert opposite effects on cellular processes that include proliferation, apoptosis and …

Estrogen has been postulated as a contributor for lung cancer development and
progression. We reviewed the current knowledge about the expression and prognostic …

Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ) belong to a superfamily of
nuclear receptors called steroid hormone receptors, which, upon binding ligand, dimerize …

While estrogen receptor β (ERβ) may impact the progression of non-small cell lung cancer
(NSCLC), its linkage to alteration of the vasculogenic mimicry (VM) formation to influence the …

Triple negative breast cancer (TNBC) is a type of aggressive breast cancer lacking the
expression of estrogen receptors (ER), progesterone receptors (PR) and human epidermal …

Inflammation is a characteristic marker in numerous lung disorders. Several immune cells,
such as macrophages, dendritic cells, eosinophils, as well as T and B lymphocytes …

Increasing evidence indicates that estrogen promotes tumor growth in both estrogen target
organs and non-target organs. Estrogen regulates cell proliferation and differentiation via …

Lung cancer has long been thought of as a cancer that mainly affects men, but over the past
several decades, because of the high increase in tobacco use by women, there has been a …

Steroid receptors existing outside the nucleus are increasingly being recognized in many
organs and cell types, impacting the biology of bone, the heart and blood vessels, and the …

Steroid receptors (SRs) are members of the nuclear receptor family, which are ligand-
activated transcription factors. SRs regulate many physiological functions including …