Potential inhibitors targeting papain-like protease of SARS-CoV-2: two birds with one stone
H Jiang, P Yang, J Zhang - Frontiers in chemistry, 2022 - frontiersin.org
Severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2), the pathogen of the
Coronavirus disease-19 (COVID-19), is still devastating the world causing significant chaos …
Coronavirus disease-19 (COVID-19), is still devastating the world causing significant chaos …
Antiviral effects of phytochemicals against severe acute respiratory syndrome coronavirus 2 and their mechanisms of action: A review
The worldwide spreading of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐
2) has posed a serious threat to health, economic, environmental, and social aspects of …
2) has posed a serious threat to health, economic, environmental, and social aspects of …
Bioactive compounds from mangosteen (Garcinia mangostana L.) as an antiviral agent via dual inhibitor mechanism against SARSCoV-2: an in silico approach
Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is the virus that causes
COVID-19 which is responsible for respiratory illness infection in humans. The virus was first …
COVID-19 which is responsible for respiratory illness infection in humans. The virus was first …
Antiviral activity of natural phenolic compounds in complex at an allosteric site of SARS-CoV-2 papain-like protease
V Srinivasan, H Brognaro, PR Prabhu… - Communications …, 2022 - nature.com
Abstract SARS-CoV-2 papain-like protease (PLpro) covers multiple functions. Beside the
cysteine-protease activity, facilitating cleavage of the viral polypeptide chain, PLpro has the …
cysteine-protease activity, facilitating cleavage of the viral polypeptide chain, PLpro has the …
PeruNPDB: The Peruvian natural products database for in silico drug screening
HL Barazorda-Ccahuana, LG Ranilla… - Scientific Reports, 2023 - nature.com
Since the number of drugs based on natural products (NPs) represents a large source of
novel pharmacological entities, NPs have acquired significance in drug discovery. Peru is …
novel pharmacological entities, NPs have acquired significance in drug discovery. Peru is …
Computational approaches to define poncirin from Magnolia champaka leaves as a novel multi-target inhibitor of SARS-CoV-2
SM Patil, B Phanindra, PS Shirahatti… - Journal of …, 2023 - Taylor & Francis
Phytochemical-based drug discovery against the severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) has been the focus of the current scenario. In this context, we …
coronavirus-2 (SARS-CoV-2) has been the focus of the current scenario. In this context, we …
Autochthonous Peruvian Natural Plants as Potential SARS-CoV-2 Mpro Main Protease Inhibitors
MN Peralta-Moreno, V Anton-Muñoz… - Pharmaceuticals, 2023 - mdpi.com
Over 750 million cases of COVID-19, caused by the Severe Acute Respiratory Syndrome
Coronavirus 2 (SARS-CoV-2), have been reported since the onset of the global outbreak …
Coronavirus 2 (SARS-CoV-2), have been reported since the onset of the global outbreak …
A comprehensive update of various attempts by medicinal chemists to combat COVID-19 through natural products
The ongoing COVID-19 pandemic has resulted in a global panic because of its continual
evolution and recurring spikes. This serious malignancy is caused by the severe acute …
evolution and recurring spikes. This serious malignancy is caused by the severe acute …
[HTML][HTML] Virtual screening of substances used in the treatment of SARS-CoV-2 infection and analysis of compounds with known action on structurally similar proteins …
PA Negru, DC Miculas, T Behl, AF Bungau… - Biomedicine & …, 2022 - Elsevier
Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is considered
the etiological agent of the disease that caused the COVID-19 pandemic, and for which …
the etiological agent of the disease that caused the COVID-19 pandemic, and for which …
[HTML][HTML] Computer-aided drug design approaches applied to screen natural product's structural analogs targeting arginase in Leishmania spp
HL Barazorda-Ccahuana, LD Goyzueta-Mamani… - …, 2023 - ncbi.nlm.nih.gov
Introduction: Leishmaniasis is a disease with high mortality rates and approximately 1.5
million new cases each year. Despite the new approaches and advances to fight the …
million new cases each year. Despite the new approaches and advances to fight the …