Assessment of Microvascular Disease in Heart and Brain by MRI: Application in Heart Failure with Preserved Ejection Fraction and Cerebral Small Vessel Disease
The objective of this review is to investigate the commonalities of microvascular (small
vessel) disease in heart failure with preserved ejection fraction (HFpEF) and cerebral small …
vessel) disease in heart failure with preserved ejection fraction (HFpEF) and cerebral small …
Contextualizing the Role of Osteopontin in the Inflammatory Responses of Alzheimer's Disease
Alzheimer's disease (AD) is characterized by progressive accumulations of extracellular
amyloid-beta (Aβ) aggregates from soluble oligomers to insoluble plaques and …
amyloid-beta (Aβ) aggregates from soluble oligomers to insoluble plaques and …
Serum Brevican as a Biomarker of Cerebrovascular Disease in an Elderly Cognitively Impaired Cohort
In the brain, the extracellular matrix (ECM) composition shapes the neuronal
microenvironment and can undergo substantial changes with cerebral pathology. Brevican …
microenvironment and can undergo substantial changes with cerebral pathology. Brevican …
Developing blood-brain barrier arterial spin labelling as a non-invasive early biomarker of Alzheimer's disease (DEBBIE-AD): a prospective observational multicohort …
Introduction Loss of blood-brain barrier (BBB) integrity is hypothesised to be one of the
earliest microvascular signs of Alzheimer's disease (AD). Existing BBB integrity imaging …
earliest microvascular signs of Alzheimer's disease (AD). Existing BBB integrity imaging …
[HTML][HTML] Distinct effects of blood pressure parameters on Alzheimer's and vascular markers in 1,952 Asian individuals without dementia
S Lee, SE Kim, H Jang, JP Kim, G Sohn… - … Research & Therapy, 2024 - ncbi.nlm.nih.gov
Background Risk factors for cardiovascular disease, including elevated blood pressure, are
known to increase risk of Alzheimer's disease. There has been increasing awareness of the …
known to increase risk of Alzheimer's disease. There has been increasing awareness of the …
Independent effect of Aβ burden on cognitive impairment in patients with small subcortical infarction
SH Kang, M Kang, JH Han, ES Lee, KJ Lee… - Alzheimer's Research & …, 2023 - Springer
Background The effect of amyloid-β (Aβ) on cognitive impairment in patients with small
subcortical infarction remains controversial, although a growing body of evidence shows a …
subcortical infarction remains controversial, although a growing body of evidence shows a …
Interaction Between Arteriosclerosis and-β on Cognitive Function
I Frentz, J van Arendonk, AE Leeuwis… - Journal of …, 2024 - content.iospress.com
Background: Dementia is a multifactorial disease, with Alzheimer's disease (AD) and
vascular pathology often co-occurring in many individuals with dementia. Yet, the interplay …
vascular pathology often co-occurring in many individuals with dementia. Yet, the interplay …
[HTML][HTML] Protocol: Developing blood-brain barrier arterial spin labelling as a non-invasive early biomarker of Alzheimer's disease (DEBBIE-AD): a prospective …
Introduction Loss of blood-brain barrier (BBB) integrity is hypothesised to be one of the
earliest microvascular signs of Alzheimer's disease (AD). Existing BBB integrity imaging …
earliest microvascular signs of Alzheimer's disease (AD). Existing BBB integrity imaging …
[HTML][HTML] Small vessel disease burden and functional brain connectivity in mild cognitive impairment
Background The role of small vessel disease in the development of dementia is not yet
completely understood. Functional brain connectivity has been shown to differ between …
completely understood. Functional brain connectivity has been shown to differ between …
[HTML][HTML] 脑小血管病发病机制与神经影像学标记物的研究进展
王子涵， 鲍海华 - Advances in Clinical Medicine, 2023 - hanspub.org
脑小血管病(CSVD) 是老年人群最为常见的慢性进展性脑部疾病. CSVD 主要通过脑磁共振成像
进行识别, 尽管神经成像并不具有特异性, 但它已被广泛应用. 由于对CSVD …
进行识别, 尽管神经成像并不具有特异性, 但它已被广泛应用. 由于对CSVD …