The advanced glycation end products (AGEs) are organic molecules formed in any living
organisms with a great variety of structural and functional properties. They are considered …

Objective Use of the frailty index to measure an accumulation of deficits has been proven a
valuable method for identifying elderly people at risk for increased vulnerability, disease …

Persistent hyperglycemic state in type 2 diabetes mellitus leads to the initiation and
progression of non-enzymatic glycation reaction with proteins and lipids and nucleic acids …

The receptor for advanced glycation end products (RAGE) is a non-specific multi-ligand
pattern recognition receptor capable of binding to a range of structurally diverse ligands …

Individuals with diabetes mellitus (DM) disclose a higher incidence and a poorer prognosis
of heart failure (HF) than non-diabetic people, even in the absence of other HF risk factors …

Cellular proteins are decorated with a wide range of acetyl and other acyl modifications.
Many studies have demonstrated regulation of site-specific acetylation by acetyltransferases …

The receptor for advanced glycation end-products (RAGE) was initially characterized and
named for its ability to bind to advanced glycation end-products (AGEs) that form upon the …

Because of structural and cellular differences (ie, degrees of matrix abundance and cross-
linking, mural cell density, and adventitia), large and medium-sized vessels, in comparison …

Patients with chronic kidney disease (CKD) are more prone to oxidative stress and chronic
inflammation, which may lead to an increase in the synthesis of advanced glycation end …

A nonenzymatic reaction between reducing sugars and amino groups of proteins, lipids and
nucleic acids contributes to the aging of macromolecules and subsequently alters their …