Inhibiting effects of dietary polyphenols on chronic eye diseases

Z Xu, T Sun, W Li, X Sun - Journal of Functional Foods, 2017 - Elsevier
The prevalence of many eye diseases, including cataracts, age-related macular
degeneration and diabetic retinopathy, is expected to increase and has become leading …

[HTML][HTML] Retinal microglia are critical for subretinal neovascular formation

A Usui-Ouchi, Y Usui, T Kurihara, E Aguilar, MI Dorrell… - JCI insight, 2020 - ncbi.nlm.nih.gov
Abnormal subretinal neovascularization is a characteristic of vision-threatening retinal
diseases, including macular telangiectasia (MacTel) and retinal angiomatous proliferation …

[PDF][PDF] Resveratrol inhibits hypoxia-induced vascular endothelial growth factor expression and pathological neovascularization

CS Lee, EY Choi, SC Lee, HJ Koh… - Yonsei medical …, 2015 - synapse.koreamed.org
Purpose To investigate the effects of resveratrol on the expression of hypoxia-inducible
factor 1α (HIF-1α) and vascular endothelial growth factor (VEGF) in human adult retinal …

Angiomodulatory properties of Rhodiola spp. and other natural antioxidants

DM Radomska-Leśniewska, P Skopiński… - … European Journal of …, 2015 - termedia.pl
Disturbances of angiogenesis and oxidative stress can lead to many serious diseases such
as cancer, diabetes or ischemic heart disease. Substances neutralizing oxidative stress are …

Role of receptor-mediated endocytosis in the antiangiogenic effects of human T lymphoblastic cell-derived microparticles

C Yang, W Xiong, Q Qiu, Z Shao… - American Journal …, 2012 - journals.physiology.org
Microparticles possess therapeutic potential regarding angiogenesis. We have
demonstrated the contribution of apoptotic human CEM T lymphocyte-derived microparticles …

Polyphenols and posterior segment eye diseases: effects on angiogenesis, invasion, migration and epithelial-mesenchymal transition

M Caban, U Lewandowska - Food Reviews International, 2023 - Taylor & Francis
Posterior segment eye diseases are a major cause of visual impairment worldwide. If left
untreated, most of them lead to partial or complete blindness. The formation of new …

Resveratrol inhibits KSHV reactivation by lowering the levels of cellular EGR-1

OF Dyson, LR Walker, A Whitehouse, PP Cook… - PloS one, 2012 - journals.plos.org
In the field of herpesvirus research, the exact molecular mechanism by which such viruses
reactivate from latency remains elusive. Kaposi's sarcoma-associated herpesvirus (KSHV) …

Therapeutic Effects of Anti-Inflammatory and Anti-Oxidant Nutritional Supplementation in Retinal Ischemic Diseases

D Lee, Z Fu, A Hellstrom, LEH Smith - International Journal of Molecular …, 2024 - mdpi.com
Appropriate nutrients are essential for cellular function. Dietary components can alter the risk
of systemic metabolic diseases, including cardiovascular diseases, cancer, diabetes, and …

FE65 as a link between VLDLR and APP to regulate their trafficking and processing

SB Dumanis, KA Chamberlain, Y Jin Sohn… - Molecular …, 2012 - Springer
Background Several studies found that FE65, a cytoplasmic adaptor protein, interacts with
APP and LRP1, altering the trafficking and processing of APP. We have previously shown …

[HTML][HTML] Resveratrol for the management of diabetes and its downstream pathologies

MJ Nanjan, J Betz - European endocrinology, 2014 - ncbi.nlm.nih.gov
Over the past 10 years more than 10,000 papers and in vitro investigations have been
published that identify or analyse various critical pathways and biological processes through …