Maternal stress and medical illnesses during early life are well-documented environmental
indicators of an increased risk of schizophrenia. Few studies, conversely, have confirmed an …

Genome-wide association studies (GWAS) have reported substantial genomic loci
significantly associated with clinical risk of bipolar disorder (BD), and studies combining …

Background Reprogramming human induced pluripotent stem cells (iPSCs) from somatic
cells and generating three-dimensional brain organoids from these iPSCs provide access to …

Growing evidence supports that prenatal processes play an important role for cognitive
ability in normal and clinical conditions. In this context, several neuroimaging studies …

Communication between cells occurs through secreted molecules, among which Wnt
ligands play a critical role in balancing cell proliferation, differentiation and cellular …

The neurobiology of bipolar disorder, a chronic and systemic ailment is not completely
understood. The bipolar phenotype manifests in myriad ways, and psychopharmacological …

Background The recent widespread use of diffusion tensor imaging (DTI) tractography
allowed researchers to investigate the diffusivity modifications and neuroanatomical …

Human postmortem studies suggest a major role for abnormalities in GABAergic
interneurons in the prefrontal cortex in schizophrenia. Cortical interneurons differentiated …

Introduction Emerging evidence suggests central roles of miRNAs in the pathogenesis of
bipolar disorder (BD). Exosomes are membrane-bound vesicles acting as “biological cargo …

Background While few previous studies highlighted a higher prevalence of autistic traits
among adults with Bipolar Disorder (BD), little is known about their clinical significance in …