Background Emerging evidence indicates that poor periodontal health adversely impacts
cognition. This review examined the available longitudinal evidence concerning the effect of …

Over the past two decades, the importance of microbiota in health and disease has become
evident. The human gut microbiota and oral microbiota are the largest and second-largest …

Background Porphyromonas gingivalis (Pg), the keystone pathogen in chronic periodontitis,
is reported to initiate Alzheimer's disease pathologies in preclinical studies. However, the …

The oral cavity is the initial chamber of digestive tract; the saliva swallowed daily contains an
estimated 1.5× 1012 oral bacteria. Increasing evidence indicates that periodontal pathogens …

Periodontitis, a chronic, inflammatory disease, induces systemic inflammation and
contributes to the development of neurodegenerative diseases. The precise etiology of the …

Background: The human being is defined as a 'superorganism'since it is made up of its own
cells and microorganisms that reside inside and outside the human body. Commensal …

It has been suggested that molecular pathological mechanisms responsible for periodontitis
can be linked with biochemical alterations in neurodegenerative disorders. Hypothetically …

Imbalances of the oral microbiota and dysbiosis have traditionally been linked to the
occurrence of teeth and oral diseases. However, recent findings indicate that this microbiota …

Substantial evidence suggests that periodontal disease increases the risk of developing and
progressing extraoral manifestations such as diabetes, atherosclerosis, rheumatoid arthritis …

Gut dysbiosis and psychiatric symptoms are common early manifestations of Alzheimer's
disease (AD) and Parkinson's disease (PD). These diseases, characterised by progressive …