Osteoarthritis (OA) is a highly prevalent whole-joint disease that causes disability and pain
and affects a patient's quality of life. However, currently, there is a lack of effective early …

Sufficient bone volume is indispensable to achieve functional and aesthetic results in the
fields of oral oncology, trauma, and implantology. Currently, guided bone regeneration …

Angiogenesis is closely coupled with osteogenesis and has equal importance. Thus,
promoting angiogenesis during the bone repair process is vital for ideal bone regeneration …

Angiogenesis, well-coupled with osteogenesis, plays an indispensable and vital role in
modulating hard tissue regeneration. Thus, simultaneously promoting osteogenesis and …

Gelatin methacryloyl (GelMA) hydrogels is a widely used bioink because of its good
biological properties and tunable physicochemical properties, which has been widely used …

To treat bone defects, repairing the nerve‐rich periosteum is critical for repairing the local
electric field. In this study, an endogenous electric field is coupled with 2D black phosphorus …

Repairing large segment bone defects is still a clinical challenge. Bone tissue prefabrication
shows great translational potentials and has been gradually accepted clinically. Existing …

Aim To determine the effect of secretome hypoxia mesenchymal stem cells (SH-MSCs) on
the relative gene expression of hypoxia inducible factor-1a (HIF-1a) and basic fibroblast …

Background Aging is a degenerative process that is associated with an increased risk of
diseases. Intermittent hypoxia has been investigated in reference to performance and health …

The normal physiological activities and functions of bone cells cannot be separated from the
balance of the oxygenation level, and the physiological activities of bone cells are different …