To overview the present global burden of pneumococcal disease is important because new
preventive measures such as the pneumococcal conjugate vaccine 13 are currently being …

Streptococcus pneumoniae is the most common cause of community-acquired pneumonia,
meningitis, and bacteremia in children and adults. Invasive pneumococcal disease (IPD) …

Pneumococcal disease is more frequent and more deadly in persons with certain
comorbidities. We used 1999 and 2000 data from the Active Bacterial Core surveillance …

Background Pneumococcal diseases are major causes of morbidity among adults,
especially those over 50 years of age. While pneumococcal conjugated vaccines (PCV's) …

Exponentially increased risk of infectious death in older renal transplant recipients.
Background The benefit of renal transplantation for patients with end-stage renal disease …

Streptococcus pneumoniae causes significant morbidity and mortality. Children younger
than 2 years and individuals older than 65 years experience the highest rates of …

As individuals advance in age, the risk of infection, bacteremia, and mortality caused by
Streptococcus pneumoniae rises. Retrospective data demonstrate that the licensed …

Pneumococcal disease can be divided into invasive disease, ie when bacteria are detected
in normally sterile body fluids, and noninvasive disease. Pneumococcal disease occurs …

Obesity negatively affects immune function and host defense mechanisms. Obesity is
associated with chronic activation of the innate immune system and consequent local and …

Streptococcus pneumoniae cause considerable morbidity and mortality, with persistent
neurological sequelae, particularly in young children and the elderly. It is widely assumed …