Cardiovascular disease in women remains under-diagnosed and under-treated. Recent
studies suggest that this is caused, at least in part, by the lack of sex-specific diagnostic …

Heart failure is a pressing worldwide public-health problem with millions of patients having
worsening heart failure. Despite all the available therapies, the condition carries a very poor …

While ventricular electromechanics is extensively studied in both physiological and
pathological conditions, four-chamber heart models have only been addressed recently; …

Abstract Cardiac digital twins (Cardiac Digital Twin (CDT) s) of human electrophysiology
(Electrophysiology (EP)) are digital replicas of patient hearts derived from clinical data that …

Type 2 diabetes mellitus causes excessive morbidity and premature cardiovascular (CV)
mortality. Although tight glycemic control improves microvascular complications, its effects …

Metabolic pathways integrate to support tissue homeostasis and to prompt changes in cell
phenotype. In particular, the heart consumes relatively large amounts of substrate not only to …

The heart has a high rate of ATP production and turnover that is required to maintain its
continuous mechanical work. Perturbations in ATP-generating processes may therefore …

The network for cardiac fuel metabolism contains intricate sets of interacting pathways that
result in both ATP-producing and non–ATP-producing end points for each class of energy …

Although photoplethysmogram (PPG) and electrocardiogram (ECG) signals can be used to
estimate blood pressure (BP) by extracting various features, the changes in morphological …

The primary focus of monitoring anesthetized patients is the assessment of depth of
anesthesia, cardiovascular and pulmonary consequences of the anesthetized state, and …