[HTML][HTML] Lipase inhibitors for obesity: A review

TT Liu, XT Liu, QX Chen, Y Shi - Biomedicine & Pharmacotherapy, 2020 - Elsevier
With the rapid increase in the population of obese individuals, obesity has become a global
problem. Many kinds of chronic metabolic diseases easily caused by obesity have received …

Is food addictive? A review of the science

AN Gearhardt, EM Schulte - Annual Review of Nutrition, 2021 - annualreviews.org
As ultraprocessed foods (ie, foods composed of mostly cheap industrial sources of dietary
energy and nutrients plus additives) have become more abundant in our food supply, rates …

[PDF][PDF] Habitual daily intake of a sweet and fatty snack modulates reward processing in humans

SE Thanarajah, AG DiFeliceantonio, K Albus… - Cell metabolism, 2023 - cell.com
Western diets rich in fat and sugar promote excess calorie intake and weight gain; however,
the underlying mechanisms are unclear. Despite a well-documented association between …

'Liking'and 'wanting'in eating and food reward: Brain mechanisms and clinical implications

I Morales, KC Berridge - Physiology & behavior, 2020 - Elsevier
It is becoming clearer how neurobiological mechanisms generate 'liking'and
'wanting'components of food reward. Mesocorticolimbic mechanisms that enhance …

Brain–gut–microbiome interactions in obesity and food addiction

A Gupta, V Osadchiy, EA Mayer - Nature Reviews Gastroenterology & …, 2020 - nature.com
Normal eating behaviour is coordinated by the tightly regulated balance between intestinal
and extra-intestinal homeostatic and hedonic mechanisms. By contrast, food addiction is a …

Animal models of obesity and diabetes mellitus

M Kleinert, C Clemmensen, SM Hofmann… - Nature Reviews …, 2018 - nature.com
More than one-third of the worldwide population is overweight or obese and therefore at risk
of developing type 2 diabetes mellitus. In order to mitigate this pandemic, safer and more …

The dopamine motive system: implications for drug and food addiction

ND Volkow, RA Wise, R Baler - Nature Reviews Neuroscience, 2017 - nature.com
Behaviours such as eating, copulating, defending oneself or taking addictive drugs begin
with a motivation to initiate the behaviour. Both this motivational drive and the behaviours …

Dopamine and addiction

RA Wise, MA Robble - Annual review of psychology, 2020 - annualreviews.org
Addiction is commonly identified with habitual nonmedical self-administration of drugs. It is
usually defined by characteristics of intoxication or by characteristics of withdrawal …

Patchy progress on obesity prevention: emerging examples, entrenched barriers, and new thinking

CA Roberto, B Swinburn, C Hawkes, TTK Huang… - The Lancet, 2015 - thelancet.com
Despite isolated areas of improvement, no country to date has reversed its obesity epidemic.
Governments, together with a broad range of stakeholders, need to act urgently to decrease …

Early-life adversity and physical and emotional health across the lifespan: A neuroimmune network hypothesis

R Nusslock, GE Miller - Biological psychiatry, 2016 - Elsevier
Children who experience chronic stressors are vulnerable to emotional and physical health
problems across the lifespan. This phenomenon raises questions for scientists and …