Probiotics and Their Bioproducts: A Promising Approach for Targeting Methicillin-Resistant Staphylococcus aureus and Vancomycin-Resistant Enterococcus

M Jain, G Stitt, L Son, EY Enioutina - Microorganisms, 2023 - mdpi.com
Antibiotic resistance is a serious global health problem that poses a threat to the successful
treatment of various bacterial infections, especially those caused by methicillin-resistant …

Antibiotic dose optimisation in the critically ill: targets, evidence and future strategies

CJ Dyer, JJ De Waele, JA Roberts - Current Opinion in Critical …, 2024 - journals.lww.com
Antibiotic dose optimisation in the critically ill: targets, evidence and future strategies Page 1
MCC 300512 CURRENT OPINION Antibiotic dose optimisation in the critically ill: targets …

Role of microsomal metabolism in bromfenac-induced cytotoxicity

JS Jeon, H Kim, S Jo, J Sim, SK Kim - Chemico-Biological Interactions, 2024 - Elsevier
This study delves into the intricate mechanisms underlying drug-induced liver injury (DILI)
with a specific focus on bromfenac, the withdrawn nonsteroidal anti-inflammatory drug. DILI …

Unraveling the impact of therapeutic drug monitoring via machine learning for patients with sepsis

HC Ates, A Alshanawani, S Hagel, MO Cotta… - Cell Reports …, 2024 - cell.com
Clinical studies investigating the benefits of beta-lactam therapeutic drug monitoring (TDM)
among critically ill patients are hindered by small patient groups, variability between studies …

A case report of treatment of a streptococcal brain abscess with ceftobiprole supported by the measurement of drug levels in the cerebrospinal fluid

S Giuliano, J Angelini, S Flammini, P Della Siega… - Heliyon, 2024 - cell.com
In this paper, we describe the case of a patient admitted to our hospital because of a brain
abscess due to Streptococcus intermedius. The management of brain abscess is …

Beta‐lactam antibiotic concentrations in critically ill patients with standard and adjusted dosages: A prospective observational study

I Areskog Lejbman, G Torisson… - Acta …, 2024 - Wiley Online Library
Introduction Antibiotic concentration target attainment is known to be poor in critically ill
patients. Dose adjustment is recommended in patients with altered clearance, obesity and …

Improving cefazolin exposure in critically ill children using a population pharmacokinetic model

C Rivaud, M Oualha, E Salvador, E Bille… - British Journal of …, 2024 - Wiley Online Library
Aims Population pharmacokinetics (PK) models may be effective in improving antibiotic
exposure with individualized dosing. The aim of the study is to assess cefazolin exposure …

Unraveling the Impact of Therapeutic Drug Monitoring via Machine Learning

HC Ates, A Alshanawani, S Hagel, MO Cotta… - medRxiv, 2023 - medrxiv.org
Clinical studies investigating the benefits of beta-lactam therapeutic drug monitoring (TDM)
among critically ill patients have been hindered by small patient group, variability between …

Antibiotic-induced neurological adverse drug reactions

C Lacroix, T Pietri, V Montero, T Soeiro, F Rouby… - Therapies, 2024 - Elsevier
Antibiotics are drugs widely used all around the world. Central nervous system adverse drug
reactions (CNS ADRs) are mostly under-suspected with antibiotics. Nevertheless, these …

Contaminants in Honey: Safeguarding Quality and Consumer Health

K Kaur, P Arora, G Gupta - UTTAR …, 2024 - science.researchersasian.com
Honey, produced largely by European Honey Bees, Apis mellifera. It possesses qualities
that can be used to cure cancer, wounds, and ailments. The presence of environmental …