[HTML][HTML] Adipokines and proinflammatory cytokines, the key mediators in the pathogenesis of nonalcoholic fatty liver disease

S Stojsavljević, MG Palčić, LV Jukić… - World journal of …, 2014 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is a condition in which excess fat accumulates in
the liver of a patient with no history of alcohol abuse or other causes for secondary hepatic …

[HTML][HTML] Non-alcoholic fatty liver disease: what the clinician needs to know

MV Machado, H Cortez-Pinto - World journal of gastroenterology …, 2014 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is the most frequent cause of liver disease in the
Western world. Furthermore, it is increasing worldwide, paralleling the obesity pandemic …

Obesity, insulin resistance, NASH and hepatocellular carcinoma

J Yu, J Shen, TT Sun, X Zhang, N Wong - Seminars in cancer biology, 2013 - Elsevier
Epidemiological and clinical data have clearly demonstrated that non-alcoholic
steatohepatitis (NASH) predisposes risk to the development of hepatocellular carcinoma …

Recent advances in nonalcoholic fatty liver disease

O Cheung, AJ Sanyal - Current opinion in gastroenterology, 2010 - journals.lww.com
The underlying mechanism and pathogenesis of NAFLD remain elusive despite ongoing
researches to make significant advances in the understanding of its natural history …

The genetic interactions between non-alcoholic fatty liver disease and cardiovascular diseases

NWS Chew, B Chong, CH Ng, G Kong, YH Chin… - Frontiers in …, 2022 - frontiersin.org
The ongoing debate on whether non-alcoholic fatty liver disease (NAFLD) is an active
contributor or an innocent bystander in the development of cardiovascular disease (CVD) …

[HTML][HTML] Genetic background in nonalcoholic fatty liver disease: a comprehensive review

FS Macaluso, M Maida, S Petta - World Journal of …, 2015 - ncbi.nlm.nih.gov
In the Western world, nonalcoholic fatty liver disease (NAFLD) is considered as one of the
most significant liver diseases of the twenty-first century. Its development is certainly driven …

Body mass index and the visceral adipose tissue expression of IL-6 and TNF-alpha are associated with the morphological severity of non-alcoholic fatty liver disease …

ASB Jorge, JMO Andrade, AF Paraíso… - Obesity research & …, 2018 - Elsevier
Objectives To analyze the mRNA expression of interleukin-6 (IL-6) and tumour necrosis
factor-alpha (TNF-α) in the liver and white adipose tissue samples of individuals with class III …

[HTML][HTML] Genomic aspects of NAFLD pathogenesis

A Naik, D Rozman - Genomics, 2013 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is the most predominant liver disease worldwide
and hepatic manifestation of the metabolic syndrome. Its histology spectrum ranges from …

Genetic association of IL-6, TNF-α and SDF-1 polymorphisms with serum cytokine levels in diabetic foot ulcer

U Dhamodharan, V Viswanathan, E Krishnamoorthy… - Gene, 2015 - Elsevier
Abstract The IL-6− 174G/C (rs1800795), TNF-α− 308G/A (rs1800629) and− 238 G/A
(rs361525) and SDF-1 801 G/A (rs1801157) are well characterized SNPs which have …

[HTML][HTML] Genetic, metabolic and environmental factors involved in the development of liver cirrhosis in Mexico

O Ramos-Lopez, E Martinez-Lopez… - World journal of …, 2015 - ncbi.nlm.nih.gov
Liver cirrhosis (LC) is a chronic illness caused by inflammatory responses and progressive
fibrosis. Globally, the most common causes of chronic liver disease include persistent …