Intermittent fasting in the prevention and treatment of cancer

KK Clifton, CX Ma, L Fontana… - CA: a cancer journal for …, 2021 - Wiley Online Library
Chronic caloric restriction (CR) has powerful anticarcinogenic actions in both preclinical and
clinical studies but may be difficult to sustain. As an alternative to CR, there has been …

[HTML][HTML] Obesity and cancer mechanisms: tumor microenvironment and inflammation

NM Iyengar, A Gucalp, AJ Dannenberg… - Journal of clinical …, 2016 - ncbi.nlm.nih.gov
Purpose There is growing evidence that inflammation is a central and reversible mechanism
through which obesity promotes cancer risk and progression. Methods We review recent …

Cancer-cell-secreted extracellular vesicles suppress insulin secretion through miR-122 to impair systemic glucose homeostasis and contribute to tumour growth

M Cao, R Isaac, W Yan, X Ruan, L Jiang, Y Wan… - Nature cell …, 2022 - nature.com
Epidemiological studies demonstrate an association between breast cancer (BC) and
systemic dysregulation of glucose metabolism. However, how BC influences glucose …

Physical activity, biomarkers, and disease outcomes in cancer survivors: a systematic review

R Ballard-Barbash, CM Friedenreich… - Journal of the …, 2012 - academic.oup.com
Background Cancer survivors often seek information about how lifestyle factors, such as
physical activity, may influence their prognosis. We systematically reviewed studies that …

The role of adiponectin in cancer: a review of current evidence

M Dalamaga, KN Diakopoulos… - Endocrine …, 2012 - academic.oup.com
Excess body weight is associated not only with an increased risk of type 2 diabetes and
cardiovascular disease (CVD) but also with various types of malignancies. Adiponectin, the …

Obesity, leptin and breast cancer: epidemiological evidence and proposed mechanisms

S Andò, L Gelsomino, S Panza, C Giordano… - Cancers, 2019 - mdpi.com
The prevalence of obesity has been steadily increasing over the past few decades in several
developed and developing countries, with resultant hazardous health implications …

Obesity-associated Breast Cancer: Analysis of risk factors

A Engin - Obesity and lipotoxicity, 2017 - Springer
Several studies show that a significantly stronger association is obvious between increased
body mass index (BMI) and higher breast cancer incidence. Furthermore, obese women are …

Inflammation and increased aromatase expression occur in the breast tissue of obese women with breast cancer

PG Morris, CA Hudis, D Giri, M Morrow… - Cancer prevention …, 2011 - AACR
Obesity is a risk factor for the development of hormone receptor–positive breast cancer in
postmenopausal women and has been associated with an increased risk of recurrence and …

Diabetes and cancer: two diseases with obesity as a common risk factor

SK Garg, H Maurer, K Reed… - Diabetes, Obesity and …, 2014 - Wiley Online Library
There is a growing body of evidence to support a connection between diabetes
(predominantly type 2), obesity and cancer. Multiple meta‐analyses of epidemiological data …

Obesity and cancer: local and systemic mechanisms

NM Iyengar, CA Hudis… - Annual review of …, 2015 - annualreviews.org
Obesity is a leading modifiable risk factor for the development of several epithelial
malignancies. In addition to increasing risk, obesity also confers worse prognosis for many …