Context Prostate-specific membrane antigen (PSMA) is a promising molecular target for
prostate cancer (PCa) that has allowed the development of a novel diagnostic approach to …

The skeleton is one of the most common sites for metastatic disease, particularly from breast
and prostate cancer. Bone metastases are associated with considerable morbidity, and …

Bone is a common metastasis site in several malignancies, most importantly prostate and
breast cancers. Given the significance of the early and accurate diagnosis of bone …

Purpose Defining an optimal imaging modality for assessment of therapy and the best time
of evaluation are pivotal for ideal patient's management. Methods 223 Ra (Xofigo®, formerly …

Sodium Fluoride F 18 (18F-NaF) is a positronemitting radiotracer that was first introduced in
1962 for skeletal scintigraphy. Its clinical use was limited, however, at that time mainly due to …

Cancer patients with spinal metastases are a diagnostic and treatment challenge for the
clinician. This challenge must be addressed through a multidisciplinary, multimodal, and …

Purpose: Vertebral compression fractures frequently present with back pain and are
determined by magnetic resonance (MR) imaging. However, fluorodeoxyglucose positron …

Aim Cancer is the third leading cause of mortality worldwide, the second in developed
countries, and represents 13% of all deaths in the world [1]. Approximately 70% of patients …