The urothelium: life in a liquid environment
The urothelium, which lines the renal pelvis, ureters, urinary bladder, and proximal urethra,
forms a high-resistance but adaptable barrier that surveils its mechanochemical …
forms a high-resistance but adaptable barrier that surveils its mechanochemical …
Toilet-based continuous health monitoring using urine
S Tasoglu - Nature Reviews Urology, 2022 - nature.com
Regular health monitoring can result in early detection of disease, accelerate the delivery of
medical care and, therefore, considerably improve patient outcomes for countless medical …
medical care and, therefore, considerably improve patient outcomes for countless medical …
[PDF][PDF] Proteomic and metabolomic profiling of urine uncovers immune responses in patients with COVID-19
X Bi, W Liu, X Ding, S Liang, Y Zheng, X Zhu, S Quan… - Cell reports, 2022 - cell.com
The utility of the urinary proteome in infectious diseases remains unclear. Here, we analyzed
the proteome and metabolome of urine and serum samples from patients with COVID-19 …
the proteome and metabolome of urine and serum samples from patients with COVID-19 …
VEGF signalling inhibition-induced proteinuria: mechanisms, significance and management
H Izzedine, C Massard, JP Spano, F Goldwasser… - European Journal of …, 2010 - Elsevier
Proteinuria is a dose-related side-effect occurring after inhibition of vascular endothelial
growth factor (VEGF) signalling and may reflect severe glomerular damage. The inhibition of …
growth factor (VEGF) signalling and may reflect severe glomerular damage. The inhibition of …
Molecular signatures of obstructive sleep apnea in adults: a review and perspective
ES Arnardottir, M Mackiewicz, T Gislason, KL Teff… - Sleep, 2009 - academic.oup.com
The consequences of obstructive sleep apnea (OSA) are largely mediated by chronic
intermittent hypoxia and sleep fragmentation. The primary molecular domains affected are …
intermittent hypoxia and sleep fragmentation. The primary molecular domains affected are …
[HTML][HTML] Nanoparticles in the diagnosis and treatment of vascular aging and related diseases
H Xu, S Li, YS Liu - Signal Transduction and Targeted Therapy, 2022 - nature.com
Aging-induced alternations of vasculature structures, phenotypes, and functions are key in
the occurrence and development of vascular aging-related diseases. Multiple molecular and …
the occurrence and development of vascular aging-related diseases. Multiple molecular and …
Urinary markers of tubular injury in early diabetic nephropathy
Diabetic nephropathy (DN) is a common and serious complication of diabetes associated
with adverse outcomes of renal failure, cardiovascular disease, and premature mortality …
with adverse outcomes of renal failure, cardiovascular disease, and premature mortality …
Diabetic nephropathy: traditional to proteomic markers
RN Moresco, MB Sangoi, JAM De Carvalho, E Tatsch… - Clinica chimica acta, 2013 - Elsevier
Diabetic nephropathy (DN) is one of the major microvascular complications of diabetes and
it is defined as a rise in the urinary albumin excretion (UAE) rate and abnormal renal …
it is defined as a rise in the urinary albumin excretion (UAE) rate and abnormal renal …
[HTML][HTML] Urine proteome profiling predicts lung cancer from control cases and other tumors
C Zhang, W Leng, C Sun, T Lu, Z Chen, X Men… - …, 2018 - thelancet.com
Abstract Development of noninvasive, reliable biomarkers for lung cancer diagnosis has
many clinical benefits knowing that most of lung cancer patients are diagnosed at the late …
many clinical benefits knowing that most of lung cancer patients are diagnosed at the late …
Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT)
Exosomes are membrane vesicles that are secreted by cells upon fusion of multivesicular
bodies with the plasma membrane. Exosomal proteomics has emerged as a powerful …
bodies with the plasma membrane. Exosomal proteomics has emerged as a powerful …