Endophenotypes in psychopathology research: where do we stand?

GA Miller, B Rockstroh - Annual Review of Clinical Psychology, 2013 - annualreviews.org
Endophenotypes for psychopathology have been conceived as latent, unobserved, but
measureable manifestations of phenomena that causally connect genetic liability to clinical …

[图书][B] Behavioral genetics

R Plomin - 2008 - books.google.com
Behavioral Genetics, Fifth Edition provides an engaging and clear overview of human and
animal behavioral genetics that is designed to introduce students in the behavioral …

Behavioral genetics

AC DeVries, RJ Nelson - Handbook of psychophysiology, 2007 - books.google.com
Behavioral genetics is the study of the relationship between genes and behavior. There are
four main issues addressed by this scientific discipline:(1) understanding the extent to which …

Regional gray matter deficits in alcohol dependence: A meta-analysis of voxel-based morphometry studies

PR Xiao, ZY Dai, JG Zhong, YL Zhu, HC Shi… - Drug and alcohol …, 2015 - Elsevier
Background Many studies have revealed a widespread pattern of gray matter (GM) atrophy
by using voxel-based morphometry (VBM) studies involving the pathophysiology of alcohol …

Meta-analysis of six genes (BDNF, DRD1, DRD3, DRD4, GRIN2B and MAOA) involved in neuroplasticity and the risk for alcohol dependence

DA Forero, S Lopez-Leon, HD Shin, BL Park… - Drug and alcohol …, 2015 - Elsevier
Background Alcohol-related problems have a large impact on human health, accounting for
around 4% of deaths and 4.5% of disability-adjusted life-years around the world. Genetic …

Consortium on Vulnerability to Externalizing Disorders and Addictions (cVEDA): A developmental cohort study protocol

E Sharma, N Vaidya, U Iyengar, Y Zhang, B Holla… - BMC psychiatry, 2020 - Springer
Background Low and middle-income countries like India with a large youth population
experience a different environment from that of high-income countries. The Consortium on …

Ethanol-induced cerebellar ataxia: cellular and molecular mechanisms

MS Dar - The Cerebellum, 2015 - Springer
The cerebellum is an important target of ethanol toxicity given that cerebellar ataxia is the
most consistent physical manifestation of acute ethanol consumption. Despite the …

Opposite actions of alcohol on tonic GABAA receptor currents mediated by nNOS and PKC activity

JS Kaplan, C Mohr, DJ Rossi - Nature neuroscience, 2013 - nature.com
The molecular mechanisms that mediate genetic variability in response to alcohol are
unclear. We found that alcohol had opposite actions (enhancement or suppression) on …

Effects of cigarette smoking history on neurocognitive recovery over 8 months of abstinence in alcohol‐dependent individuals

TC Durazzo, DL Pennington, TP Schmidt… - Alcoholism: Clinical …, 2014 - Wiley Online Library
Background This study compared the rate and extent of recovery on measures of learning
and memory, processing speed, and working memory in treatment‐seeking alcohol …

Psychological and neurobiological precursors of alcohol use disorders in high-risk youth

SY Hill, J O'Brien - Current Addiction Reports, 2015 - Springer
It has long been known that alcohol use disorders (AUDs) run in families with substantial
heritability. Determining the specific genetic underpinnings of these disorders has been …