[HTML][HTML] Imaging calcium in neurons

C Grienberger, A Konnerth - Neuron, 2012 - cell.com
Calcium ions generate versatile intracellular signals that control key functions in all types of
neurons. Imaging calcium in neurons is particularly important because calcium signals exert …

[HTML][HTML] Zebrafish: an emerging real-time model system to study Alzheimer's disease and neurospecific drug discovery

S Saleem, RR Kannan - Cell death discovery, 2018 - nature.com
Zebrafish (Danio rerio) is emerging as an increasingly successful model for translational
research on human neurological disorders. In this review, we appraise the high degree of …

Brain-wide neuronal dynamics during motor adaptation in zebrafish

MB Ahrens, JM Li, MB Orger, DN Robson, AF Schier… - Nature, 2012 - nature.com
A fundamental question in neuroscience is how entire neural circuits generate behaviour
and adapt it to changes in sensory feedback. Here we use two-photon calcium imaging to …

Guidelines on nicotine dose selection for in vivo research

SG Matta, DJ Balfour, NL Benowitz, RT Boyd… - …, 2007 - Springer
Rationale This review provides insight for the judicious selection of nicotine dose ranges
and routes of administration for in vivo studies. The literature is replete with reports in which …

Modeling anxiety using adult zebrafish: a conceptual review

A Stewart, S Gaikwad, E Kyzar, J Green, A Roth… - …, 2012 - Elsevier
Zebrafish (Danio rerio) are rapidly emerging as a useful animal model in neurobehavioral
research. Mounting evidence shows the suitability of zebrafish to model various aspects of …

[HTML][HTML] Prey capture behavior evoked by simple visual stimuli in larval zebrafish

IH Bianco, AR Kampff, F Engert - Frontiers in systems neuroscience, 2011 - frontiersin.org
Understanding how the nervous system recognizes salient stimuli in the environment and
selects and executes the appropriate behavioral responses is a fundamental question in …

[HTML][HTML] Ca2+ indicators based on computationally redesigned calmodulin-peptide pairs

AE Palmer, M Giacomello, T Kortemme, SA Hires… - Chemistry & biology, 2006 - cell.com
The binding interface of calmodulin and a calmodulin binding peptide were reengineered by
computationally designing complementary bumps and holes. This redesign led to the …

The serotonergic system in fish

C Lillesaar - Journal of chemical neuroanatomy, 2011 - Elsevier
Abstract Neurons using serotonin (5-HT) as neurotransmitter and/or modulator have been
identified in the central nervous system in representatives from all vertebrate clades …

Measuring calcium signaling using genetically targetable fluorescent indicators

AE Palmer, RY Tsien - Nature protocols, 2006 - nature.com
Genetically encoded Ca2+ indicators allow researchers to quantitatively measure Ca2+
dynamics in a variety of experimental systems. This protocol summarizes the indicators that …

Hypocretin/orexin overexpression induces an insomnia-like phenotype in zebrafish

DA Prober, J Rihel, AA Onah, RJ Sung… - Journal of …, 2006 - Soc Neuroscience
As many as 10% of humans suffer chronic sleep disturbances, yet the genetic mechanisms
that regulate sleep remain essentially unknown. It is therefore crucial to develop simple and …