Glycoconjugates are major constituents of mammalian cells that are formed via covalent
conjugation of carbohydrates to other biomolecules like proteins and lipids and often …

The glycome describes the complete repertoire of glycoconjugates composed of
carbohydrate chains, or glycans, that are covalently linked to lipid or protein molecules …

Glycans modify lipids and proteins to mediate inter-and intramolecular interactions across all
domains of life. RNA is not thought to be a major target of glycosylation. Here, we challenge …

Glycosylation-mediated post-translational modification is critical for regulating many
fundamental processes like cell division, differentiation, immune response, and cell-to-cell …

The immune system is strictly regulated by glycosylation through the addition of highly
diverse and dynamically changing sugar structures (glycans) to the majority of immune cell …

Founder populations often show rapid divergence from source populations after colonizing
new environments. Epigenetic modifications can mediate phenotypic responses to …

Siglec-1, also known as Sialoadhesin (Sn) and CD169 is highly conserved among
vertebrates and with 17 immunoglobulin-like domains is Siglec-1 the largest member of the …

The barrier to curing Vogt–Koyanagi–Harada disease (VKH) is thought to reside in a lack of
understanding in the roles and regulations of peripheral inflammatory immune cells. Here …

Abstract Phospholipase C epsilon 1 (PLCE1) is involved in the pathogenesis of many
cancers. However, the biological role of PLCE1 in osteosarcoma (OS) is still poorly …

The monocyte adhesion to endothelial cells is an early step in chronic inflammation.
Interferon-γ (IFN-γ) is regarded as a master regulator of inflammation development …