[HTML][HTML] Therapeutic targets and biomarkers of tumor immunotherapy: response versus non-response

DR Wang, XL Wu, YL Sun - Signal transduction and targeted therapy, 2022 - nature.com
Cancers are highly complex diseases that are characterized by not only the overgrowth of
malignant cells but also an altered immune response. The inhibition and reprogramming of …

[HTML][HTML] Bone/cartilage targeted hydrogel: Strategies and applications

H Zhang, S Wu, W Chen, Y Hu, Z Geng, J Su - Bioactive materials, 2023 - Elsevier
The skeletal system is responsible for weight-bearing, organ protection, and movement.
Bone diseases caused by trauma, infection, and aging can seriously affect a patient's quality …

[HTML][HTML] A photo-triggered self-accelerated nanoplatform for multifunctional image-guided combination cancer immunotherapy

X Kang, Y Zhang, J Song, L Wang, W Li, J Qi… - Nature …, 2023 - nature.com
Precise and efficient image-guided immunotherapy holds great promise for cancer
treatment. Here, we report a self-accelerated nanoplatform combining an aggregation …

Emerging photodynamic nanotherapeutics for inducing immunogenic cell death and potentiating cancer immunotherapy

S Zhang, J Wang, Z Kong, X Sun, Z He, B Sun, C Luo… - Biomaterials, 2022 - Elsevier
Immunotherapy has emerged as a promising cancer treatment modality. Despite the rapid
progress in cancer immunotherapy, the therapeutic efficiency and clinical translation of …

Biodegradable NIR‐II Pseudo Conjugate Polymeric Nanoparticles Amplify Photodynamic Immunotherapy via Alleviation of Tumor Hypoxia and Tumor‐Associated …

J Wan, X Zhang, D Tang, T Liu, H Xiao - Advanced Materials, 2023 - Wiley Online Library
Photodynamic therapy (PDT) has achieved great success in cancer treatment. Despite its
great promise, the efficacy of photodynamic immunotherapy can be limited by the hypoxia in …

[HTML][HTML] Engineered CAR-macrophages as adoptive immunotherapies for solid tumors

C Sloas, S Gill, M Klichinsky - Frontiers in immunology, 2021 - frontiersin.org
Cellular immunotherapies represent a promising approach for the treatment of cancer.
Engineered adoptive cell therapies redirect and augment a leukocyte's inherent ability to …

Recent advances in overcoming barriers to cell‐based delivery systems for cancer immunotherapy

Y Ding, Y Wang, Q Hu - Exploration, 2022 - Wiley Online Library
Immunotherapy strategies that use cell‐based delivery systems have sparked much interest
in the treatment of malignancies, owing to their high biocompatibility, excellent tumor …

Living leukocyte‐based drug delivery systems

Y Chen, D Qin, J Zou, X Li, XD Guo, Y Tang… - Advanced …, 2023 - Wiley Online Library
Leukocytes play a vital role in immune responses, including defending against invasive
pathogens, reconstructing impaired tissue, and maintaining immune homeostasis. When the …

Harnessing anti‐tumor and tumor‐tropism functions of macrophages via nanotechnology for tumor immunotherapy

Y Zheng, Y Han, Q Sun, Z Li - Exploration, 2022 - Wiley Online Library
Reprogramming the immunosuppressive tumor microenvironment by modulating
macrophages holds great promise in tumor immunotherapy. As a class of professional …

Stimuli-responsive drug delivery systems triggered by intracellular or subcellular microenvironments

T Sun, C Jiang - Advanced Drug Delivery Reviews, 2023 - Elsevier
Drug delivery systems (DDS) triggered by local microenvironment represents the state-of-art
of nanomedicine design, where the triggering hallmarks at intracellular and subcellular …