Therapeutic strategies for COVID-19: progress and lessons learned

G Li, R Hilgenfeld, R Whitley, E De Clercq - Nature Reviews Drug …, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …

[HTML][HTML] SARS-CoV-2 variant evasion of monoclonal antibodies based on in vitro studies

MG Cox, TP Peacock, WT Harvey, J Hughes… - Nature Reviews …, 2023 - nature.com
Monoclonal antibodies (mAbs) offer a treatment option for individuals with severe COVID-19
and are especially important in high-risk individuals where vaccination is not an option …

[PDF][PDF] Receptor binding and complex structures of human ACE2 to spike RBD from omicron and delta SARS-CoV-2

P Han, L Li, S Liu, Q Wang, D Zhang, Z Xu, P Han, X Li… - Cell, 2022 - cell.com
Summary The coronavirus disease 2019 (COVID-19) pandemic continues worldwide with
many variants arising, some of which are variants of concern (VOCs). A recent VOC, omicron …

Efficacy and safety of the RBD-dimer–based COVID-19 vaccine ZF2001 in adults

L Dai, L Gao, L Tao, SR Hadinegoro… - New England journal …, 2022 - Mass Medical Soc
Background The ZF2001 vaccine, which contains a dimeric form of the receptor-binding
domain of severe acute respiratory syndrome coronavirus 2 and aluminum hydroxide as an …

Tracking SARS-CoV-2 Omicron diverse spike gene mutations identifies multiple inter-variant recombination events

J Ou, W Lan, X Wu, T Zhao, B Duan, P Yang… - … and Targeted Therapy, 2022 - nature.com
The current pandemic of COVID-19 is fueled by more infectious emergent Omicron variants.
Ongoing concerns of emergent variants include possible recombinants, as genome …

Characterisation of SARS-CoV-2 variants in Beijing during 2022: an epidemiological and phylogenetic analysis

Y Pan, L Wang, Z Feng, H Xu, F Li, Y Shen, D Zhang… - The lancet, 2023 - thelancet.com
Background Due to the national dynamic zero-COVID strategy in China, there were no
persistent local transmissions of SARS-CoV-2 in Beijing before December, 2022. However …

Effects of a prolonged booster interval on neutralization of Omicron variant

X Zhao, D Li, W Ruan, Z Chen, R Zhang… - … England Journal of …, 2022 - Mass Medical Soc
Omicron Neutralization with a Longer Booster Interval In a study involving recipients of the
Chinese inactivated vaccines and the ZF2001 protein subunit vaccine, neutralizing antibody …

High-performance multifunctional electrospun fibrous air filter for personal protection: A review

Z Shao, H Chen, Q Wang, G Kang, X Wang, W Li… - Separation and …, 2022 - Elsevier
With the increasingly serious air pollution and the rampant coronavirus disease 2019
(COVID–19), preparing high–performance air filter to achieve the effective personal …

Cellular APOBEC3A deaminase drives mutations in the SARS-CoV-2 genome

Y Nakata, H Ode, M Kubota, T Kasahara… - Nucleic Acids …, 2023 - academic.oup.com
The number of genetic variations in the SARS-CoV-2 genome has been increasing primarily
due to continuous viral mutations. Here, we report that the human APOBEC3A (A3A) cytidine …

Multistage-split ultrafine fluffy nanofibrous membrane for high-efficiency antibacterial air filtration

Z Shao, Y Chen, J Jiang, Y Xiao, G Kang… - … Applied Materials & …, 2022 - ACS Publications
Antibacterial air filtration membranes are essential for personal protection during the
pandemic of coronavirus disease 2019 (COVID-19). However, high-efficiency filtration with …