Telomere maintenance in African trypanosomes

B Li - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
Telomere maintenance is essential for genome integrity and chromosome stability in
eukaryotic cells harboring linear chromosomes, as telomere forms a specialized structure to …

Guardians of the Genome: How the Single-Stranded DNA-Binding Proteins RPA and CST Facilitate Telomere Replication

CL Olson, DS Wuttke - Biomolecules, 2024 - mdpi.com
Telomeres act as the protective caps of eukaryotic linear chromosomes; thus, proper
telomere maintenance is crucial for genome stability. Successful telomere replication is a …

[HTML][HTML] Small LEA proteins as an effective air-water interface protectant for fragile samples during cryo-EM grid plunge freezing

KM Abe, CJ Lim - bioRxiv, 2024 - ncbi.nlm.nih.gov
Sample loss due to air-water interface (AWI) interactions is a significant challenge during
cryo-electron microscopy (cryo-EM) sample grid plunge freezing. We report that small Late …

Telomere C-Strand Fill-In Machinery: New Insights into the Human CST-DNA Polymerase Alpha-Primase Structures and Functions

CJ Lim - Macromolecular Protein Complexes V: Structure and …, 2024 - Springer
Telomeres at the end of eukaryotic chromosomes are extended by a specialized set of
enzymes and telomere-associated proteins, collectively termed here the telomere …