[HTML][HTML] Emerging new therapeutic antibody derivatives for cancer treatment
S Jin, Y Sun, X Liang, X Gu, J Ning, Y Xu… - … and Targeted Therapy, 2022 - nature.com
Monoclonal antibodies constitute a promising class of targeted anticancer agents that
enhance natural immune system functions to suppress cancer cell activity and eliminate …
enhance natural immune system functions to suppress cancer cell activity and eliminate …
The making of bispecific antibodies
U Brinkmann, RE Kontermann - MAbs, 2017 - Taylor & Francis
During the past two decades we have seen a phenomenal evolution of bispecific antibodies
for therapeutic applications. The 'zoo'of bispecific antibodies is populated by many different …
for therapeutic applications. The 'zoo'of bispecific antibodies is populated by many different …
Nanoparticle-based immunochemical biosensors and assays: recent advances and challenges
We review the progress achieved during the recent five years in immunochemical
biosensors (immunosensors) combined with nanoparticles for enhanced sensitivity. The …
biosensors (immunosensors) combined with nanoparticles for enhanced sensitivity. The …
Ligand-targeted drug delivery
M Srinivasarao, PS Low - Chemical reviews, 2017 - ACS Publications
Safety and efficacy constitute the major criteria governing regulatory approval of any new
drug. The best method to maximize safety and efficacy is to deliver a proven therapeutic …
drug. The best method to maximize safety and efficacy is to deliver a proven therapeutic …
The global landscape of approved antibody therapies
X Lyu, Q Zhao, J Hui, T Wang, M Lin… - Antibody …, 2022 - academic.oup.com
Antibody therapies have become an important class of therapeutics in recent years as they
have exhibited outstanding efficacy and safety in the treatment of several major diseases …
have exhibited outstanding efficacy and safety in the treatment of several major diseases …
The role of myeloid cells in cancer therapies
Recent clinical trials have demonstrated the ability to durably control cancer in some
patients by manipulating T lymphocytes. These immunotherapies are revolutionizing cancer …
patients by manipulating T lymphocytes. These immunotherapies are revolutionizing cancer …
Tumor abnormality-oriented nanomedicine design
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
Biosensors for whole-cell bacterial detection
A Ahmed, JV Rushworth, NA Hirst… - Clinical microbiology …, 2014 - Am Soc Microbiol
Bacterial pathogens are important targets for detection and identification in medicine, food
safety, public health, and security. Bacterial infection is a common cause of morbidity and …
safety, public health, and security. Bacterial infection is a common cause of morbidity and …
[HTML][HTML] The history of monoclonal antibody development–progress, remaining challenges and future innovations
JKH Liu - Annals of medicine and surgery, 2014 - Elsevier
As medicine progresses into a new era of personalised therapy, the use of monoclonal
antibodies to treat a wide range of diseases lies at the heart of this new forefront. Since the …
antibodies to treat a wide range of diseases lies at the heart of this new forefront. Since the …
[HTML][HTML] Design and production of bispecific antibodies
With the current biotherapeutic market dominated by antibody molecules, bispecific
antibodies represent a key component of the next-generation of antibody therapy. Bispecific …
antibodies represent a key component of the next-generation of antibody therapy. Bispecific …