Interpreting the wealth of rare genetic variants discovered in population-scale sequencing
efforts and deciphering their associations with human health and disease present a critical …

Parkinson's disease and dementia with Lewy bodies are neurodegenerative disorders
characterized by accumulation of α-synuclein (α-syn). Recently, single-chain fragment …

Patients receiving high-dose methotrexate (HDMTX) for malignancies are exposed to
diverse complications, including nephrotoxicity, hepatotoxicity, mucositis, myelotoxicity …

The concept of biomaterials has evolved from one of inert mechanical supports with a long‐
term, biologically inactive role in the body into complex matrices that exhibit selective cell …

Acute myeloid leukemia (AML) is a biologically and clinically heterogeneous disease with a
dismal prognosis and limited treatment options. Chimeric antigen receptor (CAR) T cells …

Oncolytic viruses have found a good place in the treatment of cancer. Administering
oncolytic viruses directly or by applying genetic changes can be effective in cancer treatment …

Clostridioides difficile (C. difficile), known as the major cause of antibiotic-associated
diarrhea, is regarded as one of the most common healthcare-associated bacterial infections …

Cancer is one of the most important causes of death all over the world, which has not yet
been treated efficiently. Although several therapeutic approaches have been used, some …

Single domain antibodies (VHHs) are potentially disruptive therapeutics, with important
biological value for treatment of several diseases, including neurological disorders …

Antibodies play a crucial role in the defense mechanism countering pathogens or foreign
antigens in eukaryotes. Its potential as an analytical and diagnostic tool has been exploited …