Unravelling tumour heterogeneity by single-cell profiling of circulating tumour cells
Single-cell technologies have contributed to unravelling tumour heterogeneity, now
considered a hallmark of cancer and one of the main causes of tumour resistance to cancer …
considered a hallmark of cancer and one of the main causes of tumour resistance to cancer …
Tumor heterogeneity in breast cancer
G Turashvili, E Brogi - Frontiers in medicine, 2017 - frontiersin.org
Breast cancer is a heterogeneous disease and differs greatly among different patients
(intertumor heterogeneity) and even within each individual tumor (intratumor heterogeneity) …
(intertumor heterogeneity) and even within each individual tumor (intratumor heterogeneity) …
Liquid biopsy in prostate cancer management—Current challenges and future perspectives
Simple Summary Prostate cancer (PCa) is a widespread malignancy, representing the
second leading cause of cancer-related death in men. In the last years, liquid biopsy has …
second leading cause of cancer-related death in men. In the last years, liquid biopsy has …
Cell fusion potentiates tumor heterogeneity and reveals circulating hybrid cells that correlate with stage and survival
CE Gast, AD Silk, L Zarour, L Riegler, JG Burkhart… - Science …, 2018 - science.org
High lethality rates associated with metastatic cancer highlight an urgent medical need for
improved understanding of biologic mechanisms driving metastatic spread and identification …
improved understanding of biologic mechanisms driving metastatic spread and identification …
Circulating tumor cells predict survival in early average-to-high risk breast cancer patients
B Rack, C Schindlbeck, J Jückstock… - Journal of the …, 2014 - academic.oup.com
Abstract Background Circulating tumor cells (CTCs) have been shown to predict reduced
survival outcomes in metastatic breast cancer. Methods CTCs were analyzed in 2026 …
survival outcomes in metastatic breast cancer. Methods CTCs were analyzed in 2026 …
Circulating tumor cells and circulating tumor DNA: challenges and opportunities on the path to clinical utility
Recent technological advances have enabled the detection and detailed characterization of
circulating tumor cells (CTC) and circulating tumor DNA (ctDNA) in blood samples from …
circulating tumor cells (CTC) and circulating tumor DNA (ctDNA) in blood samples from …
Isolation of circulating tumor cells using a microvortex-generating herringbone-chip
Rare circulating tumor cells (CTCs) present in the bloodstream of patients with cancer
provide a potentially accessible source for detection, characterization, and monitoring of …
provide a potentially accessible source for detection, characterization, and monitoring of …
[HTML][HTML] Challenges in circulating tumor cell detection by the CellSearch system
KC Andree, G van Dalum, LWMM Terstappen - Molecular oncology, 2016 - Elsevier
Enumeration and characterization of circulating tumor cells (CTC) hold the promise of a real
time liquid biopsy. They are however present in a large background of hematopoietic cells …
time liquid biopsy. They are however present in a large background of hematopoietic cells …
Circulating tumor cells: approaches to isolation and characterization
Circulating tumor cells (CTCs) shed from primary and metastatic cancers are admixed with
blood components and are thus rare, making their isolation and characterization a major …
blood components and are thus rare, making their isolation and characterization a major …
Circulating tumor cells, disease progression, and survival in metastatic breast cancer
Background We tested the hypothesis that the level of circulating tumor cells can predict
survival in metastatic breast cancer. Methods In a prospective, multicenter study, we tested …
survival in metastatic breast cancer. Methods In a prospective, multicenter study, we tested …