Sex and gender issues in multiple sclerosis

HF Harbo, R Gold, M Tintoré - Therapeutic advances in …, 2013 - journals.sagepub.com
Multiple sclerosis (MS) is universally found to be more prevalent in women than men. This
has led to extensive studies of differences in the immune system or nervous system between …

Cerebrospinal fluid oligoclonal bands in multiple sclerosis and clinically isolated syndromes: a meta-analysis of prevalence, prognosis and effect of latitude

R Dobson, S Ramagopalan, A Davis… - Journal of Neurology …, 2013 - jnnp.bmj.com
Background Oligoclonal bands (OCBs) unique to the cerebrospinal fluid are used in the
diagnosis of multiple sclerosis (MS). The precise prevalence of OCBs in MS and clinically …

The genetics of multiple sclerosis: an up‐to‐date review

PA Gourraud, HF Harbo, SL Hauser… - Immunological …, 2012 - Wiley Online Library
Multiple sclerosis (MS) is a prevalent inflammatory disease of the central nervous system
that often leads to disability in young adults. Treatment options are limited and often only …

New perspectives in the natural history of multiple sclerosis

H Tremlett, Y Zhao, P Rieckmann, M Hutchinson - Neurology, 2010 - AAN Enterprises
Multiple sclerosis (MS) has entered an era of immunomodulatory drug treatment, the impact
of which on long-term disease progression remains controversial. The increasing use of …

The evidence for a role of B cells in multiple sclerosis

G Disanto, JM Morahan, MH Barnett, G Giovannoni… - Neurology, 2012 - AAN Enterprises
Understanding the pathogenesis of complex immunologic disorders such as multiple
sclerosis (MS) is challenging. Abnormalities in many different cell types are observed in the …

Secondary progression in multiple sclerosis: neuronal exhaustion or distinct pathology?

C Larochelle, T Uphaus, A Prat, F Zipp - Trends in neurosciences, 2016 - cell.com
Prevention of progression in neurological diseases, particularly in multiple sclerosis (MS)
but also in neurodegenerative diseases, remains a significant challenge. MS patients switch …

Diagnosis and management of secondary-progressive multiple sclerosis: time for change

J Oh, K Alikhani, T Bruno, V Devonshire… - Neurodegenerative …, 2019 - Taylor & Francis
Identifying the transition of relapsing-remitting multiple sclerosis (MS) to the secondary-
progressive MS form remains a clinical challenge due to the gradual nature of the transition …

Can CSF biomarkers predict future MS disease activity and severity?

R Magliozzi, AH Cross - Multiple Sclerosis Journal, 2020 - journals.sagepub.com
Multiple sclerosis (MS) is a heterogeneous disease. With several disease modifying
treatments of different mechanisms of action in use now and in development, it is important …

Multiple sclerosis patients lacking oligoclonal bands in the cerebrospinal fluid have less global and regional brain atrophy

D Ferreira, O Voevodskaya, K Imrell, L Stawiarz… - Journal of …, 2014 - Elsevier
To investigate whether multiple sclerosis (MS) patients with and without cerebrospinal fluid
(CSF) oligoclonal immunoglobulin G bands (OCB) differ in brain atrophy. Twenty-eight OCB …

Recent progress in epidemiology, clinical features, and therapy of multiple sclerosis in China

M Wang, C Liu, M Zou, Z Niu… - Therapeutic Advances …, 2023 - journals.sagepub.com
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system
characterized by inflammation, demyelination, and neurodegeneration. It mainly affects …