The hormone receptor oestrogen receptor-α (ER) orchestrates physiological mammary
gland development, breast carcinogenesis and the progression of breast tumours into lethal …

Antibody-drug conjugates (ADCs) have emerged as a revolutionary therapeutic class,
combining the precise targeting ability of monoclonal antibodies with the potent cytotoxic …

Simple Summary Despite the increased use of neoadjuvant chemotherapy in the early
setting of breast cancer, there is a clinical need for predictive markers of response in daily …

Breast cancer is the most common cancer affecting women worldwide. It is a malignant and
heterogeneous disease with distinct molecular subtypes, which has prognostic and …

Simple Summary Breast cancer is the most common cancer and leading cause of death
worldwide. Therefore, it is important to diagnose and treat breast cancer early. Current …

Stratification of recurrence risk is a cornerstone of early breast cancer diagnosis that informs
a patient's optimal treatment pathway. Several tools exist that combine clinicopathological …

Identifying novel circulating biomarkers predictive of response and informative about the
mechanisms of resistance, is the new challenge for breast cancer (BC) management. The …

Breast cancer management has witnessed significant advancements, especially in the
diagnosis and treatment response monitoring through the implementation of imaging …

Simple Summary The aim of this review is to evaluate the present status of the use of cell-
free DNA and its fraction of circulating tumor DNA (ctDNA) because this year July 2022, an …

Circulating tumour DNA (ctDNA) detection via liquid biopsy is an emerging alternative to
tissue biopsy, but its potential in treatment response monitoring and prognosis in triple …