Challenges in the use of animal models and perspectives for a translational view of stress and psychopathologies
NCB Barroca, G Della Santa, D Suchecki… - Neuroscience & …, 2022 - Elsevier
The neurobiology and development of treatments for stress-related neuropsychiatric
disorders rely heavily on animal models. However, the complexity of these disorders makes …
disorders rely heavily on animal models. However, the complexity of these disorders makes …
Anti-anxiety properties of selected medicinal plants
Exploration of new drugs targeting anxiety treatment is a major concern worldwide.
Medicinal plants are being used as a potential source of novel drugs for anxiety disorders …
Medicinal plants are being used as a potential source of novel drugs for anxiety disorders …
CB1 receptor signalling mediates cannabidiol-induced panicolytic-like effects and defensive antinociception impairment in mice threatened by Bothrops jararaca …
BM de Paula Rodrigues… - Journal of …, 2022 - journals.sagepub.com
Background: Cannabis sativa-derived substances such as cannabidiol (CBD) have attracted
increasing clinical interest and consist in a new perspective for treating some neurological …
increasing clinical interest and consist in a new perspective for treating some neurological …
[HTML][HTML] Delivery of graphene oxide nanosheets modulates glutamate release and normalizes amygdala synaptic plasticity to improve anxiety-related behavior
Graphene oxide nanosheets (GO) were reported to alter neurobiological processes
involving cell membrane dynamics. GO ability to reversibly downregulate specifically …
involving cell membrane dynamics. GO ability to reversibly downregulate specifically …
Defensive behaviors and brain regional activation changes in rats confronting a snake
In the present study, we examined behavioral and brain regional activation changes of rats).
To a nonmammalian predator, a wild rattler snake (Crotalus durissus terrificus). Accordingly …
To a nonmammalian predator, a wild rattler snake (Crotalus durissus terrificus). Accordingly …
[HTML][HTML] Graphene oxide prevents lateral amygdala dysfunctional synaptic plasticity and reverts long lasting anxiety behavior in rats
AF Biagioni, G Cellot, E Pati, N Lozano, B Ballesteros… - Biomaterials, 2021 - Elsevier
Engineered small graphene oxide (s-GO) sheets were previously shown to reversibly down-
regulate glutamatergic synapses in the hippocampus of juvenile rats, disclosing an …
regulate glutamatergic synapses in the hippocampus of juvenile rats, disclosing an …
The rodent-versus-wild snake paradigm as a model for studying anxiety-and panic-like behaviors: face, construct and predictive validities
T Paschoalin-Maurin, T dos Anjos-Garcia… - Neuroscience, 2018 - Elsevier
Using an innovative approach to study the neural bases of psychiatric disorders, this study
investigated the behavioral, morphological and pharmacological bases of panic attack …
investigated the behavioral, morphological and pharmacological bases of panic attack …
Investigating the effect of parental pre-gestational stress on ethological parameters in male rat offspring
Although extensive research has focused on the impact of maternal stress during
pregnancy, there remains a significant gap in understanding the influence of pre-pregnancy …
pregnancy, there remains a significant gap in understanding the influence of pre-pregnancy …
[HTML][HTML] Conditioned flight response in female rats to naturalistic threat is estrous-cycle dependent
Despite the prevalent expression of freezing behavior following Pavlovian fear conditioning,
a growing body of literature suggests potential sex differences in defensive responses. Our …
a growing body of literature suggests potential sex differences in defensive responses. Our …
Reduced perineuronal net expression in Fmr1 KO mice auditory cortex and amygdala is linked to impaired fear-associated memory
SM Reinhard, M Rais, S Afroz, Y Hanania… - Neurobiology of learning …, 2019 - Elsevier
Abstract Fragile X Syndrome (FXS) is a leading cause of heritable intellectual disability and
autism. Humans with FXS show anxiety, sensory hypersensitivity and impaired learning. The …
autism. Humans with FXS show anxiety, sensory hypersensitivity and impaired learning. The …